Wu Tao, Xing Yanchun
Department of Urology, Huangshan City People's Hospital, Huangshan , 245000, China.
Department of Medicine, Huangshan Vocational Technical College, Huangshan, 245000, China.
Open Med (Wars). 2024 Oct 2;19(1):20241039. doi: 10.1515/med-2024-1039. eCollection 2024.
We conducted a systematic review to compare the diagnostic utility of ultrasound-guided transperineal (TP) and transrectal (TR) prostate biopsy methods for prostate cancer detection.
We searched PubMed, Embase, Web of Science, and Cochrane databases up to October 30, 2023, for relevant studies, screening the literature and assessing bias independently.
Eleven trials were analyzed using relative risk and 95% confidence intervals, with no evidence of publication bias. Diagnostic rates showed no significant difference between TP and TR biopsies (mean difference [MD]: 1.03, 95% confidence interval [CI]: 0.91-1.14, = 0.56). Prostate volume analysis also showed no significant difference (MD: -0.07, 95% CI: -0.73 to 0.59, < 0.0001, combined effect size = 0.83). Similarly, PSA levels were comparable between TP and TR biopsies (MD: 0.93, 95% CI: -0.44 to 2.30, < 0.0001, combined effect size = 0.18).
Both biopsy methods exhibit similar diagnostic accuracy; however, TP has a lower risk of biopsy.
我们进行了一项系统评价，以比较超声引导下经会阴（TP）和经直肠（TR）前列腺穿刺活检方法在前列腺癌检测中的诊断效用。
我们检索了截至2023年10月30日的PubMed、Embase、Web of Science和Cochrane数据库，查找相关研究，独立筛选文献并评估偏倚。
使用相对风险和95%置信区间对11项试验进行了分析，没有发表偏倚的证据。TP和TR活检之间的诊断率没有显著差异（平均差[MD]：1.03，95%置信区间[CI]：0.91 - 1.14，P = 0.56）。前列腺体积分析也没有显著差异（MD：-0.07，95% CI：-0.73至0.59，P < 0.0001，合并效应量I² = 0.83）。同样，TP和TR活检之间的前列腺特异性抗原（PSA）水平相当（MD：0.93，95% CI：-0.44至2.30，P < 0.0001，合并效应量I² = 0.18）。
两种活检方法的诊断准确性相似；然而，TP活检的风险较低。
