Varshney Anchal, Bhargava Manish, Raj Pratijya
Department of Oral Pathology and Microbiology, Manav Rachna Dental College, Faridabad, IND.
Department of Oral Pathology, Manav Rachna Dental College, Faridabad, IND.
Cureus. 2024 Sep 8;16(9):e68938. doi: 10.7759/cureus.68938. eCollection 2024 Sep.
The term "unicystic ameloblastoma" describes cystic lesions that exhibit radiographic, clinical, or gross characteristics of a jaw cyst. However, histologic examination reveals a typical ameloblastomatous epithelium lining the cyst cavity, with or without luminal and/or mural tumor proliferation. Unicystic ameloblastoma is a less prevalent kind of ameloblastoma. Among the odontogenic cysts, neoplastic transformation is highest in odontogenic keratocysts (OKCs) and dentigerous cysts (DCs). Calretinin is considered a specific immunohistochemical marker for neoplastic ameloblastic epithelium and serves as a diagnostic tool for differentiating odontogenic cystic lesions from ameloblastic tumors. This paper illustrates a case of a DC transforming into unicystic ameloblastoma in a 22-year-old male patient using the immunohistochemical expression of calretinin.
术语“单囊性成釉细胞瘤”描述的是具有颌骨囊肿的影像学、临床或大体特征的囊性病变。然而，组织学检查显示囊肿腔内衬有典型的成釉细胞瘤上皮，有或无腔内和/或壁内肿瘤增殖。单囊性成釉细胞瘤是一种不太常见的成釉细胞瘤。在牙源性囊肿中，牙源性角化囊肿（OKC）和含牙囊肿（DC）的肿瘤性转化发生率最高。钙视网膜蛋白被认为是肿瘤性成釉细胞上皮的一种特异性免疫组化标志物，可作为区分牙源性囊性病变和成釉细胞瘤性肿瘤的诊断工具。本文通过钙视网膜蛋白的免疫组化表达，阐述了一名22岁男性患者中含牙囊肿转变为单囊性成釉细胞瘤的病例。
