了解局部免疫以实现区域化医疗。
Understanding local immunity to enable regionalized medicine.
作者信息
De Giovanni Marco, Inverso Donato, Iannacone Matteo
机构信息
Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Vita-Salute San Raffaele University, Milan, Italy.
出版信息
EMBO J. 2024 Dec;43(23):5788-5792. doi: 10.1038/s44318-024-00255-6. Epub 2024 Oct 9.
Abstract
The adaptation of immune cells to their local microenvironments in our body is central to tissue homeostasis and linked to disease. In this commentary, we envision how future therapeutics could leverage local immunity to selectively target specific niches for disease treatment.
摘要
免疫细胞对我们体内局部微环境的适应对于组织稳态至关重要，且与疾病相关。在本评论中，我们设想未来的治疗方法如何利用局部免疫来选择性地靶向特定微环境以治疗疾病。
Zotero 插件