Guo Zai-Qiang, Gu Shun-Yi, Tian Zhi-Hua, Du Bo-Ying
Department of Science and Education, Beijing Fengtai Hospital of Integrated Traditional Chinese and Modern Medicine, Beijing, China.
Department of Internal Medicine, Beijing Tongzhou District Integrated Traditional Chinese and Modern Medicine, Beijing, China.
Front Med (Lausanne). 2024 Sep 25;11:1437731. doi: 10.3389/fmed.2024.1437731. eCollection 2024.
This review summarizes the research progress over the past 30 years on the relationship between infection and chronic respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), and bronchiectasis. is a common cause of community-acquired pneumonia, particularly in children and young adults. Key findings from recent studies indicate that infection is associated with a higher risk of asthma exacerbations and may contribute to the development of bronchiectasis in susceptible individuals. Additionally, emerging evidence suggests that -induced immune dysregulation plays a crucial role in the pathogenesis of chronic lung diseases. This review aims to summarize the current understanding of the potential links between pneumonia and various chronic respiratory conditions, including asthma, chronic obstructive pulmonary disease (COPD), and bronchiectasis. We discuss the epidemiological data, pathogenic mechanisms, clinical manifestations, and long-term consequences of -related respiratory illnesses. Additionally, we highlight the challenges in diagnosis and treatment, as well as future research directions in this field.
本综述总结了过去30年关于感染与慢性呼吸道疾病（如哮喘、慢性阻塞性肺疾病（COPD）和支气管扩张症）之间关系的研究进展。[原文此处有个未明确的词]是社区获得性肺炎的常见病因，尤其在儿童和年轻人中。近期研究的主要发现表明，[原文此处有个未明确的词]感染与哮喘急性加重的较高风险相关，并且可能促使易感个体发生支气管扩张症。此外，新出现的证据表明，[原文此处有个未明确的词]诱导的免疫失调在慢性肺部疾病的发病机制中起关键作用。本综述旨在总结目前对[原文此处有个未明确的词]肺炎与各种慢性呼吸道疾病（包括哮喘、慢性阻塞性肺疾病（COPD）和支气管扩张症）之间潜在联系的理解。我们讨论了[原文此处有个未明确的词]相关呼吸道疾病的流行病学数据、致病机制、临床表现和长期后果。此外，我们强调了诊断和治疗方面的挑战以及该领域未来的研究方向。
