Servicio de Gastroenterología, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico.
Servicio de Gastroenterología, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico; Departamento de clínicas médicas, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico.
Rev Gastroenterol Mex (Engl Ed). 2024 Oct-Dec;89(4):506-512. doi: 10.1016/j.rgmxen.2024.10.001. Epub 2024 Oct 9.
Chronic nausea and vomiting syndrome is a disorder of gut-brain interaction that affects the productive-age population. Our aim was to determine the association of this disorder with quality of life, workplace performance, and socioeconomic impact related to gastrointestinal health.
A cross-sectional study on a Mexican population was conducted. The patients were classified as having chronic nausea and vomiting syndrome or other disorders of gut-brain interaction. A comparative analysis of quality of life, workplace productivity, annual medical consultations, and digestive health-related expenses was carried out, applying a logistic regression model.
One thousand patients were included, 79.2% of whom met the criteria for a disorder of gut-brain interaction. Of the 792 patients, 10.3% presented with chronic nausea and vomiting syndrome. Said syndrome was associated with a negative impact on usual activities (OR 4.34, 95% CI 1.90-9.30, p ≤ 0.001), pain/discomfort (OR 2.09, 95% CI 1.31-3.33, p ≤ 0.001), anxiety/depression (OR 2.08, 95% CI 1.30-3.40, p ≤ 0.001), workplace presenteeism (OR 3.96, 95% CI 2.47-6.44, p ≤ 0.001), and workplace absenteeism (OR 2.54, 95% CI 1.52-4.16, p ≤ 0.001). There was also a higher number of annual medical consultations for digestive health (p = 0.013), without generating a greater annual expense due to digestive health (p = 0.08).
Chronic nausea and vomiting syndrome produces a negative impact on quality of life, which could be secondary to its symptomatology or its association with anxiety and depression.
慢性恶心和呕吐综合征是一种影响育龄人群的胃肠道-大脑相互作用障碍。我们的目的是确定这种疾病与生活质量、工作场所表现以及与胃肠道健康相关的社会经济影响之间的关联。
对墨西哥人群进行了一项横断面研究。将患者分为慢性恶心和呕吐综合征或其他胃肠道-大脑相互作用障碍。对生活质量、工作场所生产力、年度医疗咨询次数和与消化健康相关的费用进行了比较分析，并应用逻辑回归模型。
共纳入 1000 名患者，其中 79.2%符合胃肠道-大脑相互作用障碍的标准。在 792 名患者中，10.3%患有慢性恶心和呕吐综合征。该综合征与日常活动受影响（OR 4.34，95%CI 1.90-9.30，p≤0.001）、疼痛/不适（OR 2.09，95%CI 1.31-3.33，p≤0.001）、焦虑/抑郁（OR 2.08，95%CI 1.30-3.40，p≤0.001）、工作场所出勤（OR 3.96，95%CI 2.47-6.44，p≤0.001）和工作场所缺勤（OR 2.54，95%CI 1.52-4.16，p≤0.001）显著相关。接受消化健康年度医疗咨询的次数也更多（p=0.013），但由于消化健康问题导致的年度费用并未增加（p=0.08）。
慢性恶心和呕吐综合征对生活质量产生负面影响，这可能是其症状或与焦虑和抑郁相关所致。
