Arboviral Diseases Branch, Division of Vector-Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, USA.
Research for Implementation Unit, The Special Programme for Research and Training in Tropical Diseases, World Health Organization, Geneva, Switzerland.
Infect Dis Poverty. 2024 Oct 11;13(1):75. doi: 10.1186/s40249-024-01239-8.
Vector-borne diseases cause morbidity and mortality globally. However, some areas are more impacted than others, especially with climate change. Controlling vectors remains the primary means to prevent these diseases, but new, more effective tools are needed. The World Health Organization (WHO) prioritized evaluating novel control methods, such as sterile insect technique (SIT) for control of Aedes-borne diseases. In response, a multiagency partnership between the U.S. Centers for Disease Control and Prevention (CDC), the Special Programme for Research and Training in Tropical Diseases (TDR), WHO, and the International Atomic Energy Agency (IAEA) supported the operational implementation and evaluation of SIT against Aedes aegypti and arboviral diseases in the Pacific through a consortium of regional partners (PAC-SIT Consortium).
A workshop was held from 2 to 6 May 2023, during which PAC-SIT country participants, researchers, and stakeholders in SIT, scientific advisory committee members, and organizational partners came together to review the principles and components of SIT, share experiences, visit field sites and the SIT facility, and officially launch the PAC-SIT project. Working in groups focused on entomology, epidemiology, and community engagement, participants addressed challenges, priorities, and needs for SIT implementation.
The PAC-SIT workshop brought together researchers and stakeholders engaged in evaluating SIT for arboviral diseases in the Pacific region and globally. This training workshop highlighted that many countries are actively engaged in building operational capacities and phased testing of SIT. The workshop identified a key need for robust larger-scale studies tied with epidemiological endpoints to provide evidence for the scalability and impact on mosquito-borne diseases.
虫媒病在全球范围内造成发病率和死亡率。然而，一些地区比其他地区受到的影响更大，尤其是气候变化的影响。控制病媒仍然是预防这些疾病的主要手段，但需要新的、更有效的工具。世界卫生组织（WHO）优先评估新的控制方法，例如利用不育昆虫技术（SIT）控制登革热媒介蚊。为此，美国疾病控制与预防中心（CDC）、热带病研究与培训特别规划署（TDR）、世界卫生组织（WHO）和国际原子能机构（IAEA）之间的一个多机构伙伴关系通过太平洋区域合作伙伴联盟（PAC-SIT 联盟）支持在太平洋地区实施和评估针对埃及伊蚊和虫媒病毒病的 SIT。
2023 年 5 月 2 日至 6 日举行了一次研讨会，来自 PAC-SIT 国家的参与者、研究人员和 SIT 的利益相关者、科学咨询委员会成员以及组织合作伙伴齐聚一堂，审查了 SIT 的原则和组成部分，分享经验，参观实地和 SIT 设施，并正式启动 PAC-SIT 项目。参与者分组专注于昆虫学、流行病学和社区参与，解决了 SIT 实施面临的挑战、优先事项和需求。
PAC-SIT 研讨会汇集了参与评估太平洋地区和全球虫媒病毒病 SIT 的研究人员和利益相关者。该培训研讨会强调，许多国家正在积极建立运营能力，并分阶段测试 SIT。研讨会确定了一个关键需求，即需要进行强有力的、规模更大的研究，并与流行病学终点联系起来，为 SIT 的可扩展性及其对蚊媒病的影响提供证据。
