[记忆性T细胞在变应性鼻炎发病机制中的研究进展]
[Research progress of memory T cells in the pathogenesis of allergic rhinitis].
作者信息
Gao Yawen, Long Bojin, Yu Shaoqing
机构信息
Department of Otorhinolaryngology Head and Neck Surgery，Tongji Hospital，School of Medicine，Tongji University，Shanghai，200065，China.
出版信息
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Oct;38(10):975-978. doi: 10.13201/j.issn.2096-7993.2024.10.018.
Abstract
Allergic rhinitis（AR） is a non-infectious chronic inflammatory disease of the nasal mucosa mainly mediated by immunoglobulin E（IgE） in atopic individuals after exposure to allergens. T cells are the core cell population. In recent years, studies have shown that memory T cells play an important role in the development of allergic rhinitis. This article reviews the pathogenesis of memory T cells in allergic rhinitis, in order to further improve the pathogenesis of allergic rhinitis and provide theoretical basis and reference for subsequent clinical drug treatment.
摘要
变应性鼻炎（AR）是一种非感染性鼻黏膜慢性炎症性疾病，主要由特应性个体暴露于变应原后，由免疫球蛋白E（IgE）介导。T细胞是核心细胞群体。近年来，研究表明记忆T细胞在变应性鼻炎的发病机制中起重要作用。本文综述记忆T细胞在变应性鼻炎中的发病机制，以期进一步完善变应性鼻炎的发病机制，为后续临床药物治疗提供理论依据和参考。
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