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单根管生物力学预备后使用氟化银氨、印楝和次氯酸钠作为根管冲洗剂的微生物减少的比较评价:一项研究。

Comparative Evaluation of Microbial Reduction Using Silver Diamine Fluoride, (Neem) and Sodium Hypochlorite as Root Canal Irrigants after Biomechanical Preparation in Uniradicular Canals: An Study.

作者信息

Raj Shruti, Sharma Anshul, Dhinsa Kavita, Saha Sonali, Yadav Gunjan, Sharma Prerna

机构信息

Department of Pedodontics and Preventive Dentistry, Sardar Patel Post Graduate Institute of Dental and Medical Sciences, Lucknow, Uttar Pradesh, India.

出版信息

Int J Clin Pediatr Dent. 2024 Jun;17(6):625-629. doi: 10.5005/jp-journals-10005-2862.

DOI:10.5005/jp-journals-10005-2862
PMID:39391141
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11463808/
Abstract

BACKGROUND

It is difficult to completely eradicate microorganisms from the infected root canal system. Intracanal irrigants seem necessary for eradication of infected tissues and microorganisms in addition to mechanical debridement. Continuous use of chemical antimicrobial agents leads to serious side effects. Therefore, the need arises for alternative agents to overcome the disadvantages of their chemical counterparts.

AIM

To evaluate and compare the antimicrobial efficacy of three endodontic irrigants against clinically isolated bacteria found in root canals containing necrotic pulp.

MATERIALS AND METHODS

Preirrigation sample were collected using sterile paper points and sent for microbial count. Chemomechanical preparation was performed, and the root canals were irrigated with 5 mL of test samples. After 3 days, the patient was recalled, and a postirrigation sample was collected and sent for microbial count.

RESULT SYNTHESIS

Both 3.8% silver diamine fluoride (SDF) and 3% sodium hypochlorite (NaOCl) showed a superior capacity to sterilize the root canals compared to the neem group.

CONCLUSION

The use of SDF as an endodontic irrigant is feasible as it effectively removes the microbes present in the canal.

CLINICAL SIGNIFICANCE

Silver diamine fluoride has not been shown to be cytotoxic or carcinogenic, unlike NaOCl, suggesting it could be used as a potential endodontic irrigant. However, few studies have evaluated the antimicrobial efficacy of SDF as an endodontic irrigant.

HOW TO CITE THIS ARTICLE

Raj S, Sharma A, Dhinsa K, Comparative Evaluation of Microbial Reduction Using Silver Diamine Fluoride, (Neem) and Sodium Hypochlorite as Root Canal Irrigants after Biomechanical Preparation in Uniradicular Canals: An Study. Int J Clin Pediatr Dent 2024;17(6):625-629.

摘要

背景

从感染的根管系统中完全根除微生物很困难。除了机械清创外,根管冲洗剂似乎对于根除感染组织和微生物是必要的。持续使用化学抗菌剂会导致严重的副作用。因此,需要替代剂来克服其化学同类物的缺点。

目的

评估和比较三种根管冲洗剂对含有坏死牙髓的根管中临床分离细菌的抗菌效果。

材料与方法

使用无菌纸尖收集冲洗前样本并送去进行微生物计数。进行化学机械预备,并用5毫升测试样本冲洗根管。3天后,召回患者,收集冲洗后样本并送去进行微生物计数。

结果综合

与印楝组相比,3.8%氟化银氨(SDF)和3%次氯酸钠(NaOCl)在根管消毒方面表现出更强的能力。

结论

使用SDF作为根管冲洗剂是可行的,因为它能有效清除根管中的微生物。

临床意义

与NaOCl不同,氟化银氨未显示出细胞毒性或致癌性,这表明它可作为一种潜在的根管冲洗剂。然而,很少有研究评估SDF作为根管冲洗剂的抗菌效果。

如何引用本文

Raj S, Sharma A, Dhinsa K, 使用氟化银氨(印楝)和次氯酸钠作为单根根管生物机械预备后根管冲洗剂的微生物减少的比较评估:一项研究。《国际临床儿科牙科学杂志》2024;17(6):625 - 629。

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Int J Clin Pediatr Dent. 2022;15(Suppl 1):S47-S51. doi: 10.5005/jp-journals-10005-2130.
2
Quantification of Bacterial DNA from Infected Human Root Canals Using qPCR and DAPI after Disinfection with Established and Novel Irrigation Protocols.使用qPCR和DAPI对采用既定及新型冲洗方案消毒后的感染人根管中的细菌DNA进行定量分析。
Materials (Basel). 2022 Mar 4;15(5):1911. doi: 10.3390/ma15051911.
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BMC Oral Health. 2021 Apr 7;21(1):175. doi: 10.1186/s12903-021-01531-1.
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