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一种使用糠氨酸测量糖化血红蛋白的特定方法。

A specific method of glycosylated hemoglobin using furosine measurement.

作者信息

Oimomi M, Nishimoto S, Matsumoto S, Hatanaka H, Ishikawa K, Baba S

出版信息

Diabetes Res Clin Pract. 1985 Dec;1(4):193-5. doi: 10.1016/s0168-8227(85)80011-5.

Abstract

In order to get an accurately specific determination of glycosylated hemoglobin (GHb-f), the furosine assay method, which can detect epsilon-amino-lysine-bound glucose, was investigated. A good correlation was found between GHb-f values obtained by this method and HbA1 values by conventional ion exchange column chromatography. It was, therefore, considered that this technique would be a new useful method for determining glycosylated hemoglobin.

摘要

为了准确特异性地测定糖化血红蛋白(GHb-f),对能够检测ε-氨基赖氨酸结合葡萄糖的呋喃西林测定法进行了研究。通过该方法获得的GHb-f值与传统离子交换柱色谱法测得的HbA1值之间发现有良好的相关性。因此,认为该技术将是一种测定糖化血红蛋白的新的有用方法。

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