Jayakrishnan S, Dua Amit, Kumar Alok
Department of Anaesthesiology & Critical Care, Army Hospital (Research & Referral), Delhi Cantt, New Delhi, India.
J Anaesthesiol Clin Pharmacol. 2024 Jul-Sep;40(3):410-415. doi: 10.4103/joacp.joacp_90_23. Epub 2023 Oct 5.
The erector spinae plane block (ESPB) is a novel regional anesthesia technique compared to the thoracic paravertebral block (TPVB) in providing postoperative pain relief in breast surgeries. Modified radical mastectomy (MRM) is a commonly performed surgery for breast cancer. The objective of the study is to compare the efficacy of ESPB and TPVB in providing postoperative pain relief after MRM.
This is a prospective randomized study conducted in a tertiary care teaching hospital. Sixty ASA I-III adult patients (age >18 years) scheduled to undergo elective unilateral MRM for breast cancer were enrolled in the study. Ultrasound-guided ESPB or TPVB with 0.25% bupivacaine was performed preoperatively on the patients randomized into two groups, namely, the ESPB and TPVB groups. All patients received patient-controlled analgesia for postoperative pain relief. Morphine consumption and Visual Analog Score (VAS) for pain were recorded at 3, 6, 12, and 24 h postoperatively.
Primarily, the mean postoperative VAS scores between the two groups at 3, 6, 12, and 24 h showed no statistical significance and were comparable when matched at different time points. However, 24-h morphine consumption was significantly more in the ESPB group ( = 0.035). Duration of block performance also showed a significant difference, with ESPB taking less time to perform ( < 0.001). The mean age and body mass index (BMI) of patients and length of hospital stay in both the groups were similar.
Both ESPB and TPVB provided adequate analgesia in patients undergoing MRM; however, TPVB had better efficacy and opioid-sparing effect when compared to ESPB.
与胸椎旁神经阻滞(TPVB)相比,竖脊肌平面阻滞(ESPB)是一种用于乳腺手术术后镇痛的新型区域麻醉技术。改良根治性乳房切除术(MRM)是一种常见的乳腺癌手术。本研究的目的是比较ESPB和TPVB在MRM术后镇痛中的效果。
这是一项在三级护理教学医院进行的前瞻性随机研究。60例计划接受择期单侧MRM治疗乳腺癌的ASA I-III级成年患者(年龄>18岁)纳入本研究。将患者随机分为两组,即ESPB组和TPVB组,术前对其进行超声引导下的ESPB或用0.25%布比卡因进行TPVB。所有患者均接受患者自控镇痛以缓解术后疼痛。术后3、6、12和24小时记录吗啡用量和疼痛视觉模拟评分(VAS)。
首先,两组在术后3、6、12和24小时的平均VAS评分无统计学意义,在不同时间点匹配时具有可比性。然而,ESPB组24小时吗啡用量显著更多(P = 0.035)。阻滞操作时间也显示出显著差异,ESPB操作时间更短(P < 0.001)。两组患者的平均年龄、体重指数(BMI)和住院时间相似。
ESPB和TPVB在接受MRM的患者中均提供了充分的镇痛效果;然而,与ESPB相比,TPVB具有更好的疗效和阿片类药物节省效应。