Papapetropoulou M, Giamarellou H
Drugs Exp Clin Res. 1985;11(11):793-5.
The antibacterial activity of gentamicin against 10 isolates of E. coli and 10 of P. aeruginosa was investigated in pooled human urine, with or without the addition of 20 g % dextrose, at pH 6. Mean values for T50 under the influence of 50 mg/ml gentamicin were 3 +/- 0.23 h vs 1.86 +/- 0.10 h and 3.5 +/- 0.08 h vs 1.56 +/- 0.13 h with an osmolality of 1200 mosm/l and 820 mosm/l respectively.
在pH值为6的人混合尿液中，研究了庆大霉素对10株大肠杆菌和10株铜绿假单胞菌的抗菌活性，尿液中添加或不添加20%（质量分数）葡萄糖。在50mg/ml庆大霉素作用下，渗透压为1200 mosm/l时T50的平均值分别为3±0.23小时和1.86±0.10小时；渗透压为820 mosm/l时，T50的平均值分别为3.5±0.08小时和1.56±0.13小时。
