Papapetropoulou M, Giamarellou H
Drugs Exp Clin Res. 1985;11(11):797-9.
the influence of various concentrations of calcium on the antibacterial activity of gentamicin in urine on 10 strains of E. coli and 10 strains of P. aeruginosa was studied in vitro. It was found that calcium has a strong antagonistic effect on gentamicin activity, particularly with regard to P. aeruginosa. This effect is greatly reduced when gentamicin concentrations are increased to levels higher than those obtained in urine under conventional treatment schedules.
研究了不同浓度的钙对庆大霉素在体外对10株大肠杆菌和10株铜绿假单胞菌尿液中抗菌活性的影响。发现钙对庆大霉素活性有很强的拮抗作用，尤其是对铜绿假单胞菌。当庆大霉素浓度增加到高于常规治疗方案下尿液中所达到的水平时，这种作用会大大降低。
