The Second Hospital of Jilin University, Changchun, Jilin Province, China.
Sci Rep. 2024 Oct 11;14(1):23837. doi: 10.1038/s41598-024-75211-9.
Diabetic retinopathy (DR) is a common complication of diabetes, with its prevalence increasing globally. While previous research has linked obesity indices such as body mass index (BMI) to DR, the association with weight-adjusted-waist index (WWI) remains unclear. Additionally, the relationship between WWI and DR has not been fully elucidated. This cross-sectional study analyzed data from the National Health and Nutrition Examination Survey (2005-2008) to investigate these associations in Americans aged 40 and above. The study included 5436 participants (2705 men and 2731 women). Weighted logistic regression analysis revealed a significant increase in DR prevalence with higher WWI and BMI values. Smooth curve analysis demonstrated a linear correlation between WWI and DR. The findings suggest that both WWI and BMI are independently associated with DR risk among older US adults, highlighting the importance of considering central obesity measures in assessing diabetic complications.
糖尿病视网膜病变（DR）是糖尿病的一种常见并发症，其患病率在全球范围内呈上升趋势。虽然之前的研究已经将体重指数（BMI）等肥胖指数与 DR 联系起来，但与体重调整腰围指数（WWI）的关联尚不清楚。此外，WWI 与 DR 之间的关系尚未完全阐明。这项横断面研究分析了 2005-2008 年全国健康和营养检查调查（NHANES）的数据，以调查美国 40 岁及以上人群中这些关联。研究纳入了 5436 名参与者（男性 2705 名，女性 2731 名）。加权逻辑回归分析显示，DR 的患病率随着 WWI 和 BMI 值的升高而显著增加。平滑曲线分析表明 WWI 与 DR 之间存在线性相关。研究结果表明，WWI 和 BMI 均与美国老年成年人的 DR 风险独立相关，这突出了在评估糖尿病并发症时考虑中心性肥胖指标的重要性。
