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活性氧凝胶促进腭部坏死快速愈合:一例病例报告及处理策略。

Rapid Healing of Palatal Necrosis with Active Oxygen Gel: A Case Report and Management Strategy.

机构信息

Department of Implant Dentistry, Latin American Institute of Dental Research and Education - ILAPEO, Curitiba, PR, Brazil.

Department of Periodontology, UniDomBosco, Curitiba, PR, Brazil.

出版信息

Am J Case Rep. 2024 Oct 15;25:e945135. doi: 10.12659/AJCR.945135.

DOI:10.12659/AJCR.945135
PMID:39402814
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11489135/
Abstract

BACKGROUND Managing unique anatomical structures, such as the nasopalatine canal, remains key for successful implant placement and long-term functionality. Topical oral oxygen therapy (TOOT) has gained attention for its antibacterial, regenerative properties, and ability to accelerate wound healing. This report presents a case of postoperative palatal necrosis successfully treated with TOOT oxygen-active gel (blue®m) CASE REPORT A 33-year-old male patient presented with the primary concern of needing rehabilitation of the anterior maxillary region. Clinical and imaging examinations revealed a deficient maxillary ridge and an enlarged incisive foramen. The treatment plan involved nasopalatine deflation with guided bone regeneration using particulate synthetic bone graft and a collagen membrane. Seven days after surgery, he returned with minimal pain but had necrotic tissue on the palate. The necrotic tissue and a portion of the contaminated biomaterial were removed, and the area was thoroughly cleansed with a saline solution. A thick layer of active oxygen gel (blue®m) was then applied to the palatal lesion. The patient was instructed to apply the gel 3 times daily for 30 days and attended follow-up appointments every 2 days. After 12 days, rapid healing and significant clinical improvement were observed, with the patient reporting no pain or sensitivity. By day 34, the lesion had fully closed, and re-epithelialization was achieved. CONCLUSIONS Our patient had complete resolution of palatal necrosis after nervus deflation using TOOT with active oxygen gel (blue®m), and this therapy seemed to accelerate the healing process.

摘要

背景

成功的种植体植入和长期功能的关键在于管理独特的解剖结构,如鼻腭管。局部口腔氧疗 (TOOT) 因其具有抗菌、再生特性以及加速伤口愈合的能力而备受关注。本报告介绍了一例使用 TOOT 氧活性凝胶 (blue®m) 成功治疗的腭部术后坏死病例。

病例报告

一名 33 岁男性患者因需要修复上颌前区而就诊。临床和影像学检查显示上颌牙槽嵴缺损和切牙孔增大。治疗计划包括经鼻腭管排气,并使用颗粒状合成骨移植物和胶原膜进行引导骨再生。术后 7 天,他返回时疼痛轻微,但上腭有坏死组织。坏死组织和部分污染的生物材料被清除,并用生理盐水彻底清洁该区域。然后在上腭病变处涂抹一层厚厚的氧活性凝胶 (blue®m)。患者被指示每天应用凝胶 3 次,持续 30 天,并每隔 2 天进行一次随访。12 天后,观察到快速愈合和显著的临床改善,患者报告无疼痛或敏感。第 34 天,病变完全闭合,上皮化完成。

结论

在使用氧活性凝胶 (blue®m) 的局部口腔氧疗治疗经鼻腭管排气后,我们的患者完全解决了腭部坏死问题,并且这种治疗似乎加速了愈合过程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ff7/11489135/a9b6280374ec/amjcaserep-25-e945135-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ff7/11489135/a34bbd87eb48/amjcaserep-25-e945135-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ff7/11489135/a860efb17639/amjcaserep-25-e945135-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ff7/11489135/d74c183ff3ff/amjcaserep-25-e945135-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ff7/11489135/a9b6280374ec/amjcaserep-25-e945135-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ff7/11489135/a34bbd87eb48/amjcaserep-25-e945135-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ff7/11489135/a860efb17639/amjcaserep-25-e945135-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ff7/11489135/d74c183ff3ff/amjcaserep-25-e945135-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ff7/11489135/a9b6280374ec/amjcaserep-25-e945135-g004.jpg

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Topical oxygen therapy as a novel strategy to promote wound healing and control the bacteria in implantology, oral surgery and periodontology: A review.局部氧疗作为促进种植学、口腔外科和牙周病学伤口愈合及控制细菌的新策略:综述
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Association of active oxygen-releasing gel and photodynamic therapy in the treatment of residual periodontal pockets in type 2 diabetic patients: A randomized controlled clinical study.
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