Shao Enhao, Tuersun Paerhatijiang, Wumaier Dilishati, Li Shuyuan, Abudula Aibibula
Xinjiang Key Laboratory for Luminescence Minerals and Optical Functional Materials, School of Physics and Electronic Engineering, Xinjiang Normal University, Urumqi 830054, China.
Department of Physics, City University of Hong Kong, Kowloon, Hong Kong, China.
Nanomaterials (Basel). 2024 Oct 4;14(19):1603. doi: 10.3390/nano14191603.
Metal nanocages exhibit localized surface plasmon resonance that strongly absorbs and scatters light at specific wavelengths, making them potentially valuable for photothermal therapy and biological imaging applications. However, investigations on metal nanocages are still confined to high-cost and small-scale synthesis. The comprehensive analysis of optical properties and optimal size parameters of metal nanocages is rarely reported. This paper simulates the effects of materials (Ag, Au, and Cu), size parameters, refractive index of the surrounding medium, and orientation on the light absorption and scattering characteristics of the nanocages using the finite-element method and the size-dependent refractive-index model for metal nanoparticles. The results show that the Ag nanocages have excellent light absorption and scattering characteristics and respond significantly to the size parameters, while the refractive index and orientation of the surrounding medium have less effect on them. The Au nanocages also possess superior light absorption properties at specific incident wavelengths. This study also identified the optimized sizes of three metal nanocages at incident light wavelengths commonly used in biomedicine; it was also found that, under deep therapy conditions, Ag nanocages in particular exhibit the highest volume absorption and scattering coefficients of 0.708 nm and 0.583 nm, respectively. These findings offer theoretical insights into preparing target nanocage particles for applications in photothermal therapy and biological imaging.
金属纳米笼表现出局域表面等离子体共振，能在特定波长强烈吸收和散射光，这使其在光热疗法和生物成像应用中具有潜在价值。然而，对金属纳米笼的研究仍局限于高成本和小规模合成。关于金属纳米笼光学性质和最佳尺寸参数的综合分析鲜有报道。本文使用有限元方法和金属纳米颗粒的尺寸相关折射率模型，模拟了材料（银、金和铜）、尺寸参数、周围介质折射率以及取向对纳米笼光吸收和散射特性的影响。结果表明，银纳米笼具有优异的光吸收和散射特性，对尺寸参数响应显著，而周围介质的折射率和取向对其影响较小。金纳米笼在特定入射波长下也具有优异的光吸收特性。本研究还确定了三种金属纳米笼在生物医学常用入射光波长下的优化尺寸；还发现，在深度治疗条件下银纳米笼尤其表现出最高的体积吸收系数和散射系数，分别为0.708纳米和0.583纳米。这些发现为制备用于光热疗法和生物成像应用的目标纳米笼颗粒提供了理论见解。
