Zeleke Sileshi Serebe, Kebede Ephrem Bekele, Zegeye Abebaw Muhabaw, Alemayehu Birlew T, Mossa Muhammed Yesuf, Tadesse Amanuel Kassa
Department of Orthopedics, University of Gondar, College of Medicine and Health Sciences, Gondar, Ethiopia.
Department of Orthopedics, University of Gondar, College of Medicine and Health Sciences, Gondar, Ethiopia.
Int J Surg Case Rep. 2024 Nov;124:110432. doi: 10.1016/j.ijscr.2024.110432. Epub 2024 Oct 10.
Lipoblastoma is a rare, benign tumor that primarily affects infants and young children, representing a small percentage of soft tissue tumors in this population. Its early diagnosis and surgical management are crucial for favorable outcomes, as lipoblastoma can lead to significant complications if left untreated.
We report the case of an 18-month-old female toddler who presented with a progressively growing, painless mass in the left medial thigh, which had developed over six months. Imaging studies, including CT and MRI, revealed a well-defined, hypodense lobulated mass consistent with lipoblastoma. Surgical excision was performed, and the mass measured approximately 7 by 6 cm. Histopathological examination confirmed the diagnosis of lipoblastoma. The patient experienced a successful recovery without recurrence during a one-year follow-up period.
Lipoblastoma typically presents as a painless subcutaneous soft tissue mass that progressively grows. Symptoms often relate to the tumor's location and size or the mass effect on surrounding structures. Imaging studies, particularly CT and MRI, play a crucial role in making a presumptive diagnosis by revealing the tumor's characteristics and components. Total excision remains the treatment of choice for lipoblastoma.
Lipoblastoma should be included in the differential diagnosis of rapidly growing, painless masses in children under three years of age. The treatment of choice is complete surgical resection of the tumor, which is crucial for achieving favorable outcomes and reducing recurrence risk.
脂肪母细胞瘤是一种罕见的良性肿瘤，主要影响婴幼儿，在该人群的软组织肿瘤中占比很小。其早期诊断和手术治疗对于取得良好预后至关重要，因为脂肪母细胞瘤若不治疗可导致严重并发症。
我们报告一例18个月大的女童病例，她左侧大腿内侧出现一个逐渐增大的无痛性肿块，已持续6个月。包括CT和MRI在内的影像学检查显示一个边界清晰、密度减低的分叶状肿块，符合脂肪母细胞瘤表现。进行了手术切除，肿块大小约为7×6厘米。组织病理学检查确诊为脂肪母细胞瘤。患者在一年的随访期内成功康复且无复发。
脂肪母细胞瘤通常表现为无痛性皮下软组织肿块且逐渐增大。症状常与肿瘤的位置、大小或对周围结构的占位效应有关。影像学检查，尤其是CT和MRI，通过显示肿瘤的特征和成分在做出初步诊断中起关键作用。完整切除仍是脂肪母细胞瘤的首选治疗方法。
脂肪母细胞瘤应纳入3岁以下儿童快速生长的无痛性肿块的鉴别诊断。首选治疗方法是完整手术切除肿瘤，这对于取得良好预后和降低复发风险至关重要。
