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病例报告:韩国济州岛猪肉消费者中的猪链球菌人类感染:人畜共患病威胁

Case Report: Streptococcus suis Human Infections among Pork Consumers in Jeju, South Korea: Zoonotic Threats.

作者信息

Kim Eui Tae, Heo Sang Taek, Yoo Jeong Rae, Kim Misun, Kim Tae Hyoung, Kim Young Ree

机构信息

Department of Microbiology and Immunology, College of Medicine, Jeju National University, Jeju, South Korea.

Department of Internal Medicine, College of Medicine, Jeju National University, Jeju, South Korea.

出版信息

Am J Trop Med Hyg. 2024 Oct 15;111(6):1243-1246. doi: 10.4269/ajtmh.24-0201. Print 2024 Dec 4.

DOI:10.4269/ajtmh.24-0201
PMID:39406213
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11619484/
Abstract

Streptococcus suis, a bacterium commonly found in pigs, causes infections in humans through direct contact with infected animals or consumption of contaminated pork products. Recently, a localized outbreak of S. suis infection in humans resulted in three confirmed cases. All three patients had some form of contact with pigs in their medical history. One patient worked at a pig farm, whereas the other two consumed raw pork soup at the same restaurant. The patients were diagnosed with septicemia, subdural empyema, and infectious spondylitis. Streptococcus suis was isolated from their blood. This study was conducted to investigate the clinical features of three patients with S. suis infection and perform a molecular biological analysis of the strains obtained from them. Subsequent investigations highlighted the potential sources for this rare but serious infection and provided insight into preventive measures.

摘要

猪链球菌是一种常见于猪身上的细菌,可通过直接接触受感染动物或食用受污染的猪肉制品导致人类感染。最近,一起人类猪链球菌感染的局部暴发导致了3例确诊病例。所有3名患者在病史中都有某种形式与猪的接触。一名患者在养猪场工作,而另外两名患者在同一家餐馆食用了生猪肉汤。这些患者被诊断为败血症、硬膜下积脓和感染性脊柱炎。从他们的血液中分离出了猪链球菌。本研究旨在调查3例猪链球菌感染患者的临床特征,并对从他们身上获得的菌株进行分子生物学分析。后续调查突出了这种罕见但严重感染的潜在来源,并为预防措施提供了见解。

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本文引用的文献

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Human Infections in Thailand: Epidemiology, Clinical Features, Genotypes, and Susceptibility.泰国的人类感染:流行病学、临床特征、基因型及易感性
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Sociocultural Factors Influencing Human Disease in Southeast Asia.影响东南亚人类疾病的社会文化因素。
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A Case of Life-Threating Infection Presented as Septic Shock and Multiple Abscesses.一例以感染性休克和多发性脓肿形式出现的危及生命的感染病例。
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Sci Rep. 2018 Sep 6;8(1):13358. doi: 10.1038/s41598-018-31598-w.
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Streptococcus suis: a re-emerging pathogen associated with occupational exposure to pigs or pork products. Part II - Pathogenesis.猪链球菌:一种与职业性接触猪或猪肉制品相关的再度出现的病原体。第二部分 - 发病机制。
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Capsular serotypes, virulence-associated genes and antimicrobial susceptibility of Streptococcus suis isolates from pigs in Korea.韩国猪源猪链球菌分离株的荚膜血清型、毒力相关基因及抗菌药物敏感性
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Epidemiology, clinical manifestations, and outcomes of Streptococcus suis infection in humans.人感染猪链球菌的流行病学、临床表现及转归
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