Muñoz-Barba Daniel, Díaz-Calvillo Pablo, de Francisco Sofía Haselgruber, Martínez-Lopez Antonio, Sánchez-Díaz Manuel, Arias-Santiago Salvador
Dermatology Unit. Hospital Universitario Virgen de las Nieves, IBS Granada, Granada, Spain.
Trichology Clinic, Hospital Universitario Virgen de las Nieves, Granada, Spain.
J Dtsch Dermatol Ges. 2024 Dec;22(12):1611-1618. doi: 10.1111/ddg.15527. Epub 2024 Oct 15.
Alopecia areata (AA) impairs quality of life. However, there is no evidence on the impact of this disease in terms of sexual dysfunction (SD). The aim of the present study was to assess the prevalence of SD and possible associated factors in a cohort of patients with AA.
A cross-sectional study was conducted in a cohort of AA patients matched with healthy controls. Sexual function was assessed using a numerical scale and gender-specific questionnaires.
A total of 60 patients with AA and 60 healthy controls were included. The prevalence of SD was higher in women with AA than in healthy controls and in men with AA (p < 0.05). Female SD was associated with younger age, shorter duration of illness and higher rates of anxiety and depression (p < 0.05). Male SD was associated with older age and greater severity of AA (p < 0.05).
Women with AA appear to have higher rates of SD than healthy controls and men with AA. Similarly, the factors associated with SD differ between men and women, with mood disturbance being of greater relevance in women, whereas disease severity seems to play a key role in men.
斑秃（AA）会损害生活质量。然而，尚无证据表明该疾病对性功能障碍（SD）的影响。本研究的目的是评估斑秃患者队列中性功能障碍的患病率及可能的相关因素。
对一组斑秃患者及匹配的健康对照进行横断面研究。使用数字量表和针对性别的问卷评估性功能。
共纳入60例斑秃患者和60例健康对照。斑秃女性患者性功能障碍的患病率高于健康对照及斑秃男性患者（p < 0.05）。女性性功能障碍与年龄较小、病程较短以及焦虑和抑郁发生率较高相关（p < 0.05）。男性性功能障碍与年龄较大及斑秃严重程度较高相关（p < 0.05）。
斑秃女性患者的性功能障碍发生率似乎高于健康对照及斑秃男性患者。同样，与性功能障碍相关的因素在男性和女性中有所不同，情绪障碍在女性中更为相关，而疾病严重程度在男性中似乎起关键作用。
