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心血管危险因素和代谢综合征对农村西班牙儿童和青少年心外膜脂肪组织厚度的影响。

Influence of Cardiovascular Risk Factors and Metabolic Syndrome on Epicardial Adipose Tissue Thickness in Rural Spanish Children and Adolescents.

机构信息

Centro de Salud de Occidente Azahara, Street Campo, 14005 Córdoba, Spain.

Grupo Investigación GC09 Nutrigenomics, Metabolic Syndrome, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Universitario Reina Sofía, 14071 Córdoba, Spain.

出版信息

Nutrients. 2024 Sep 30;16(19):3321. doi: 10.3390/nu16193321.

Abstract

UNLABELLED

The presence of visceral adipose tissue implies a higher risk of cardiovascular diseases than subcutaneous adiposity, the most dangerous heart fat. Epicardial adipose tissue (EAT) could have great potential as a detection indicator of cardiovascular diseases, although it has seldom been studied in Spanish children.

OBJECTIVE

The objective of the current research was to describe the values of EAT in a Spanish pediatric population and to investigate the associations between EAT and anthropometric measures, blood pressure, lipid and glucose profiles, and metabolic syndrome.

METHOD

An analytical cross-sectional study of elementary and high school students (aged 6 to 17) measured anthropometrics, blood pressure, lipid and glycemic profiles, and echocardiographic fat thickness. The analysis was based on regression and discriminant analysis.

RESULTS

The results of this study (N = 227) showed that the body mass index (BMI) was 20.29 ± 4.54, with an overweight set of 49.77%, and the percentage for metabolic syndrome was 5.3%. EAT was linked to being male, BMI percentile, waist circumference, waist-to-height ratio ( < 0.001), hypertension, higher low-density lipoprotein (LDL) levels, and metabolic syndrome ( < 0.05).

CONCLUSIONS

This paper argues that in children with higher elevated EAT thickness values, this correlates with cardiovascular risk factors including high blood pressure, elevated LDL levels, and metabolic syndrome.

摘要

未注明

内脏脂肪组织的存在意味着心血管疾病的风险高于皮下脂肪堆积,而后者是最危险的心脏脂肪。心外膜脂肪组织(EAT)可能具有作为心血管疾病检测指标的巨大潜力,尽管它在西班牙儿童中很少被研究。

目的

本研究的目的是描述西班牙儿科人群中 EAT 的数值,并研究 EAT 与人体测量指标、血压、血脂和血糖谱以及代谢综合征之间的关联。

方法

对小学生和高中生(6 至 17 岁)进行横断面分析,测量人体测量指标、血压、血脂和血糖谱以及超声心动图脂肪厚度。分析基于回归和判别分析。

结果

本研究的结果(N=227)显示,体重指数(BMI)为 20.29±4.54,超重组为 49.77%,代谢综合征的百分比为 5.3%。EAT 与男性、BMI 百分位数、腰围、腰高比(<0.001)、高血压、更高的低密度脂蛋白(LDL)水平和代谢综合征(<0.05)有关。

结论

本文认为,在 EAT 厚度值较高的儿童中,这与包括高血压、升高的 LDL 水平和代谢综合征在内的心血管危险因素相关。

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