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心血管危险因素和代谢综合征对农村西班牙儿童和青少年心外膜脂肪组织厚度的影响。

Influence of Cardiovascular Risk Factors and Metabolic Syndrome on Epicardial Adipose Tissue Thickness in Rural Spanish Children and Adolescents.

机构信息

Centro de Salud de Occidente Azahara, Street Campo, 14005 Córdoba, Spain.

Grupo Investigación GC09 Nutrigenomics, Metabolic Syndrome, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Universitario Reina Sofía, 14071 Córdoba, Spain.

出版信息

Nutrients. 2024 Sep 30;16(19):3321. doi: 10.3390/nu16193321.

DOI:10.3390/nu16193321
PMID:39408289
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11479227/
Abstract

UNLABELLED

The presence of visceral adipose tissue implies a higher risk of cardiovascular diseases than subcutaneous adiposity, the most dangerous heart fat. Epicardial adipose tissue (EAT) could have great potential as a detection indicator of cardiovascular diseases, although it has seldom been studied in Spanish children.

OBJECTIVE

The objective of the current research was to describe the values of EAT in a Spanish pediatric population and to investigate the associations between EAT and anthropometric measures, blood pressure, lipid and glucose profiles, and metabolic syndrome.

METHOD

An analytical cross-sectional study of elementary and high school students (aged 6 to 17) measured anthropometrics, blood pressure, lipid and glycemic profiles, and echocardiographic fat thickness. The analysis was based on regression and discriminant analysis.

RESULTS

The results of this study (N = 227) showed that the body mass index (BMI) was 20.29 ± 4.54, with an overweight set of 49.77%, and the percentage for metabolic syndrome was 5.3%. EAT was linked to being male, BMI percentile, waist circumference, waist-to-height ratio ( < 0.001), hypertension, higher low-density lipoprotein (LDL) levels, and metabolic syndrome ( < 0.05).

CONCLUSIONS

This paper argues that in children with higher elevated EAT thickness values, this correlates with cardiovascular risk factors including high blood pressure, elevated LDL levels, and metabolic syndrome.

摘要

未注明

内脏脂肪组织的存在意味着心血管疾病的风险高于皮下脂肪堆积,而后者是最危险的心脏脂肪。心外膜脂肪组织(EAT)可能具有作为心血管疾病检测指标的巨大潜力,尽管它在西班牙儿童中很少被研究。

目的

本研究的目的是描述西班牙儿科人群中 EAT 的数值,并研究 EAT 与人体测量指标、血压、血脂和血糖谱以及代谢综合征之间的关联。

方法

对小学生和高中生(6 至 17 岁)进行横断面分析,测量人体测量指标、血压、血脂和血糖谱以及超声心动图脂肪厚度。分析基于回归和判别分析。

结果

本研究的结果(N=227)显示,体重指数(BMI)为 20.29±4.54,超重组为 49.77%,代谢综合征的百分比为 5.3%。EAT 与男性、BMI 百分位数、腰围、腰高比(<0.001)、高血压、更高的低密度脂蛋白(LDL)水平和代谢综合征(<0.05)有关。

结论

本文认为,在 EAT 厚度值较高的儿童中,这与包括高血压、升高的 LDL 水平和代谢综合征在内的心血管危险因素相关。

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Pediatr Res. 2025 Jan;97(1):311-314. doi: 10.1038/s41390-024-03319-9. Epub 2024 Jun 15.
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Assessment of Epicardial Fat in Children: Its Role as a Cardiovascular Risk Factor and How It Is Influenced by Lifestyle Habits.评估儿童的心外膜脂肪:其作为心血管风险因素的作用以及生活方式习惯对其的影响。
Nutrients. 2024 Jan 31;16(3):420. doi: 10.3390/nu16030420.
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Computed tomography measured epicardial adipose tissue and psoas muscle attenuation: new biomarkers to predict major adverse cardiac events (MACE) and mortality in patients with heart disease and critically ill patients. Part I: Epicardial adipose tissue.
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Anaesthesiol Intensive Ther. 2023;55(3):141-157. doi: 10.5114/ait.2023.130922.
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Epicardial Adipose Tissue: A Piece of The Puzzle in Pediatric Hypertension.心外膜脂肪组织:小儿高血压难题中的一块拼图。
J Clin Med. 2023 Mar 12;12(6):2192. doi: 10.3390/jcm12062192.
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Urban and rural differences in frequency of fruit, vegetable, and soft drink consumption among 6-9-year-old children from 19 countries from the WHO European region.欧洲区域 19 个国家 6-9 岁儿童水果、蔬菜和软饮料摄入频率的城乡差异。
Obes Rev. 2021 Nov;22 Suppl 6:e13207. doi: 10.1111/obr.13207. Epub 2021 Jul 7.
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Epicardial Adipose Tissue: A New Cardiovascular Imaging Parameter Deeply Connected with Cardiovascular Diseases.心外膜脂肪组织:一个与心血管疾病密切相关的新型心血管成像参数。
Arq Bras Cardiol. 2020 Nov;115(5):971-972. doi: 10.36660/abc.20200309.
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