Endocrinology Section, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122 Catania, CT, Italy.
Department of Medicine and Surgery, University Kore of Enna, 94100 Enna, EN, Italy.
Nutrients. 2024 Oct 6;16(19):3397. doi: 10.3390/nu16193397.
Metabolic syndrome (MS), a cluster of cardiometabolic disorders, and sexual dysfunction are two conditions that impact a large proportion of the general population. Although they can occur independently, they are frequently linked and significantly affect people's quality of life. In recent years, research has increasingly focused on the importance of diet, particularly the Mediterranean diet (MD), in modulating sexual function due to its anti-inflammatory, antioxidant, and vasodilatory properties. In this narrative review, we examined the relationship between MS and sexual function in both men and women, with a special emphasis on the MD's therapeutic efficacy in improving sexual dysfunction. In men, MD has been shown to ameliorate erectile dysfunction, as well as several sperm parameters, perhaps leading to improved fertility. On the other hand, adherence to MD has been demonstrated to partially recover several sexual dysfunctions in women, such as those related to their menstrual cycle, menopause, endometriosis, and polycystic ovary syndrome. These favorable effects of MD have been demonstrated in both sexes also among people affected by MS. However, more targeted studies are needed to validate these data for different dietary approaches as well.
代谢综合征 (MS),一组心血管代谢紊乱,以及性功能障碍是两种影响很大一部分普通人群的病症。尽管它们可以独立发生,但它们经常相关联,并严重影响人们的生活质量。近年来,由于其具有抗炎、抗氧化和血管舒张特性,研究越来越关注饮食的重要性,特别是地中海饮食 (MD) 在调节性功能方面的作用。在这篇叙述性综述中,我们研究了 MS 和男性和女性性功能之间的关系,特别强调了 MD 在改善性功能障碍方面的治疗效果。在男性中,MD 已被证明可改善勃起功能障碍以及几种精子参数,这可能导致生育能力提高。另一方面,已经证明坚持 MD 可部分恢复女性的几种性功能障碍,例如与月经周期、更年期、子宫内膜异位症和多囊卵巢综合征相关的障碍。这些 MD 的有利影响在两性中也在患有 MS 的人群中得到了证实。然而,需要更多有针对性的研究来验证这些数据对于不同的饮食方法。