Abdel Tawab Rasha, Rajy Jihan, Abdallat Salah, Almurrawi Muna Abdula, Al Farsi Khalil, Alassaf Jehad, Alhateeti Hussni, Al Lafi Atlal, El Bahtimi Reem, Jfri Abdulhadi, Assaf Chalid
Kuwait Cancer Control Centre, Kuwait City 13001, Kuwait.
As'ad Al Hamad Dermatology Center, Ministry of Health, Kuwait City 13001, Kuwait.
Cancers (Basel). 2024 Oct 2;16(19):3380. doi: 10.3390/cancers16193380.
The high cancer burden in the Middle East and North Africa (MENA region) is coupled with an increasing cancer incidence. While the MENA region constitutes 6% of the world's population, it remains underrepresented in clinical trials. Cutaneous T-cell lymphomas (CTCLs) represent a heterogeneous group of rare extranodal non-Hodgkin lymphomas with variable clinical presentation. In the MENA region, where darker skin colors are more common than in the West, CTCL generally presents at a younger age and with distinct clinical features that necessitate special expertise and management across disciplines: rare forms of CTCL are more common (hypo- and hyperpigmented MF) and a higher prevalence of pediatric MF is noticed. The multidisciplinary approach to cancer management is growing worldwide and is necessary for the comprehensive management of CTCL. The MENA CTCL group was established with the aim of creating a collaborative environment for the diagnosis and treatment of CTCL in the region. Its first meeting was held in May 2023. The group plans to increase the global representation of the MENA region and establish CTCL registries and patient advocacy groups in the region.
中东和北非地区（MENA地区）癌症负担沉重，且癌症发病率不断上升。尽管MENA地区占世界人口的6%，但其在临床试验中的代表性仍然不足。皮肤T细胞淋巴瘤（CTCL）是一组异质性的罕见结外非霍奇金淋巴瘤，临床表现各异。在MENA地区，深色皮肤比西方更为常见，CTCL通常在较年轻时发病，具有独特的临床特征，需要跨学科的专业知识和管理：罕见形式的CTCL更为常见（色素减退和色素沉着性蕈样肉芽肿），且儿童蕈样肉芽肿的患病率较高。癌症管理的多学科方法在全球范围内不断发展，对于CTCL的综合管理是必要的。MENA CTCL小组的成立旨在为该地区CTCL的诊断和治疗创造一个协作环境。其第一次会议于2023年5月举行。该小组计划增加MENA地区在全球的代表性，并在该地区建立CTCL登记处和患者倡导团体。
