Ehlers Lars Holger, Reinstrup Nicoline Weinreich, Olesen Renée Hangaard, Holm Jens-Christian, McEwan Phil, Le Roux Carel W
Nordic Institute of Health Economics, Aarhus, Denmark.
University Hospital Holbæk, Holbæk, Denmark.
Int J Obes (Lond). 2025 Feb;49(2):246-253. doi: 10.1038/s41366-024-01650-z. Epub 2024 Oct 16.
The treatment of obesity remains underprioritized. New pharmacologic options for the treatment of obesity have shown effectiveness and safety but are not widely reimbursed. Despite the unmet need and the existence of effective prevention and treatment strategies, substantial barriers exist to effectively address obesity as a disease. The purpose of this scoping review was to investigate the barriers for decision makers in prioritizing interventions for obesity and to seek out interconnection between barriers to prevention and treatment. A scoping review was conducted using a systematic search of both scientific databases and Health Technology Assessment (HTA) databases. Studies that addressed barriers to reimbursement or prioritization of obesity treatment and prevention were included. A total of 26 articles and 14 HTAs were included. Four main barriers for decision makers to prioritize new interventions for obesity were identified: perceptions, knowledge, economics, and politics. There was a high degree of interconnectedness among barriers, as well as large overlaps between barriers in relation to bariatric surgery, pharmacologic treatments, and prevention regulation. Multiple barriers exist that impact decision makers in prioritizing interventions for treating obesity. A strong interconnectedness of the barriers was found, indicating a systems approach to improve global prioritization to address the disease. This study suggests that decision makers should carefully consider all main barriers when addressing the obesity epidemic.
肥胖症的治疗仍未得到足够重视。治疗肥胖症的新药物疗法已显示出有效性和安全性,但未得到广泛报销。尽管存在未满足的需求以及有效的预防和治疗策略,但将肥胖症作为一种疾病有效解决仍存在重大障碍。本综述的目的是调查决策者在确定肥胖症干预措施优先级时面临的障碍,并找出预防和治疗障碍之间的相互联系。通过对科学数据库和卫生技术评估(HTA)数据库进行系统检索,开展了一项综述。纳入了涉及肥胖症治疗和预防报销或优先级障碍的研究。共纳入26篇文章和14份卫生技术评估报告。确定了决策者在确定肥胖症新干预措施优先级时面临的四个主要障碍:观念、知识、经济和政治。障碍之间存在高度的相互联系,以及在减肥手术、药物治疗和预防监管方面的障碍之间存在很大重叠。存在多种障碍影响决策者确定肥胖症治疗干预措施的优先级。发现障碍之间存在很强的相互联系,这表明需要采用系统方法来提高全球对该疾病的优先级确定。这项研究表明,决策者在应对肥胖症流行时应仔细考虑所有主要障碍。