Gulinac Milena, Miteva Dimitrina Georgieva, Peshevska-Sekulovska Monika, Novakov Ivan P, Antovic Svetozar, Peruhova Milena, Snegarova Violeta, Kabakchieva Plamena, Assyov Yavor, Vasilev Georgi, Sekulovski Metodija, Lazova Snezhina, Tomov Latchezar, Velikova Tsvetelina
Department of General and Clinical Pathology, Medical University of Plovdiv, Plovdiv 4000, Bulgaria.
Department of Genetics, Sofia University "St. Kliment Ohridski", Faculty of Biology, Sofia 1164, Bulgaria.
World J Clin Cases. 2023 Jul 6;11(19):4504-4512. doi: 10.12998/wjcc.v11.i19.4504.
Dietary imbalance and overeating can lead to an increasingly widespread disease - obesity. Aesthetic considerations aside, obesity is defined as an excess of adipose tissue that can lead to serious health problems and can predispose to a number of pathological changes and clinical diseases, including diabetes; hypertension; atherosclerosis; coronary artery disease and stroke; obstructive sleep apnea; depression; weight-related arthropathies and endometrial and breast cancer. A body weight 20% above ideal for age, gender and height is a severe health risk. Bariatric surgery is a set of surgical methods to treat morbid obesity when other treatments such as diet, increased physical activity, behavioral changes and drugs have failed. The two most common procedures currently used are sleeve gastrectomy and gastric bypass. This procedure has gained popularity recently and is generally considered safe and effective. Although current data show that perioperative mortality is low and better control of comorbidities and short-term complications is achieved, more randomized trials are needed to evaluate the long-term outcomes of bariatric procedures. This review aims to synthesize and summarize the growing evidence on the long-term effectiveness, outcomes and complications of bariatric surgery.
饮食不均衡和暴饮暴食会导致一种日益普遍的疾病——肥胖症。抛开审美因素不谈,肥胖症被定义为脂肪组织过多,这会导致严重的健康问题,并可能引发一些病理变化和临床疾病,包括糖尿病、高血压、动脉粥样硬化、冠状动脉疾病和中风、阻塞性睡眠呼吸暂停、抑郁症、与体重相关的关节病以及子宫内膜癌和乳腺癌。体重超过按年龄、性别和身高计算的理想体重20%会带来严重的健康风险。减肥手术是在节食、增加体育活动、行为改变和药物等其他治疗方法均无效时,用于治疗病态肥胖症的一系列手术方法。目前最常用的两种手术是袖状胃切除术和胃旁路手术。这种手术最近越来越受欢迎,一般被认为是安全有效的。尽管目前的数据表明围手术期死亡率较低,并且能够更好地控制合并症和短期并发症,但仍需要更多的随机试验来评估减肥手术的长期效果。这篇综述旨在综合和总结关于减肥手术长期有效性、效果和并发症的越来越多的证据。