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生姜在化疗患者恶心管理中的作用。

Role of Ginger in management of nausea among patients receiving chemotherapy.

作者信息

Syed Zamin Abbas, Fahim Ammad, Safdar Mahpara, Imtiaz Rafia

机构信息

Zamin Abbas Syed, Principal (Nursing and Midwifery), Health Services Academy, Islamabad, Pakistan.

Ammad Fahim, Director ORIC, Indus Hopsital Health Network, Karachi, Pakistan.

出版信息

Pak J Med Sci. 2024 Oct;40(9):2036-2040. doi: 10.12669/pjms.40.9.8739.

Abstract

OBJECTIVE

Cancer patients treated with chemotherapy often face variety of side effects, with nausea and vomiting being the most frequent. Ginger (), contains natural compounds that can speed up the metabolism and increase intestinal motility. It is traditionally used to treat gastrointestinal disorders. The objective of this study was to evaluate the role of ginger in management of nausea among patients receiving chemotherapy.

METHODS

This crossover interventional study was conducted to evaluate the role of ginger in management of nausea among patients receiving chemotherapy. Study was carried out at chemotherapy daycare of Shifa International Hospital Islamabad, with a sample size of 90 patients, using non-probability convenient sampling. Patients undergoing chemotherapy were given the dose of ginger (550 mg twice a day) for five consecutive days. On the next chemo cycle the same patients were given the placebo capsules of same color and weight for two times a day for five days. Patients and attendants were contacted for five days and being asked about post-chemotherapy nausea. Nausea and vomiting were measured by Rhodes scale.

RESULTS

Results showed that Rhodes score of patients taking Ginger capsules was significantly lower than those taking placebo (p-value < 0.05) in all the five days.

CONCLUSION

Ginger significantly managed the nausea among patients receiving chemotherapy. Its natural antiemetic properties provide a convenient and safe way to reduce the post-chemotherapy nausea and vomiting.

摘要

目的

接受化疗的癌症患者常常面临各种副作用,其中恶心和呕吐最为常见。生姜含有能加速新陈代谢和增强肠道蠕动的天然化合物。传统上,生姜用于治疗胃肠道疾病。本研究的目的是评估生姜在接受化疗患者恶心管理中的作用。

方法

本交叉干预研究旨在评估生姜在接受化疗患者恶心管理中的作用。研究在伊斯兰堡希法国际医院化疗日间病房进行,样本量为90例患者,采用非概率方便抽样。接受化疗的患者连续五天服用生姜剂量(550毫克,每日两次)。在下一个化疗周期,给同一批患者服用相同颜色和重量的安慰剂胶囊,每日两次,共五天。在五天内联系患者及其陪护人员,询问化疗后恶心情况。恶心和呕吐通过罗兹量表进行测量。

结果

结果显示,在所有五天中,服用生姜胶囊患者的罗兹评分显著低于服用安慰剂的患者(p值<0.05)。

结论

生姜显著缓解了接受化疗患者的恶心症状。其天然的止吐特性为减轻化疗后恶心和呕吐提供了一种方便且安全的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e33/11476162/cc40164e0340/PJMS-40-2036-g001.jpg

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