Yasue T
Arch Dermatol. 1986 Jan;122(1):66-70.
Of 66 patients with systemic lupus erythematosus (SLE), 11 (16.7%) had livedoid vasculitis. The sites of predilection included the elbows, knees, fingers, soles, and back, which are not those of common livedoid vasculitis. Livedoid vasculitis developed in ten (90.9%) of the 11 patients with SLE who eventually developed central nervous system (CNS) lupus. In contrast, such preceding livedoid vasculitis occurred in only three (11.5%) of the 26 patients with severe nephrotic lupus nephritis. Livedoid vasculitis did not occur in any patient with neither CNS lupus nor severe lupus nephritis. These results indicate that livedoid vasculitis in SLE is a very important cutaneous manifestation that may possibly be prodromal to CNS lupus.
在66例系统性红斑狼疮（SLE）患者中，11例（16.7%）患有类脂质渐进性坏死性血管炎。好发部位包括肘部、膝部、手指、足底和背部，这些并非常见类脂质渐进性坏死性血管炎的好发部位。在最终发生中枢神经系统（CNS）狼疮的11例SLE患者中，有10例（90.9%）出现了类脂质渐进性坏死性血管炎。相比之下，在26例重症狼疮性肾炎伴肾病综合征的患者中，仅有3例（11.5%）出现了上述前驱性类脂质渐进性坏死性血管炎。在既无CNS狼疮也无重症狼疮性肾炎的患者中，未出现类脂质渐进性坏死性血管炎。这些结果表明，SLE中的类脂质渐进性坏死性血管炎是一种非常重要的皮肤表现，可能是CNS狼疮的前驱症状。
