Trempe C L, Weiter J J, Furukawa H
Arch Ophthalmol. 1986 Jan;104(1):93-5. doi: 10.1001/archopht.1986.01050130103031.
One hundred thirty eyes of 126 patients with idiopathic macular holes were studied by means of indirect ophthalmoscopy, biomicroscopy, color fundus photography, and fluorescein angiography. Posterior vitreous detachment was absent in 61% of these eyes; opacities interpreted as opercula were found in 78 eyes (60%). Forty-nine fellow eyes were followed up for a mean period of 47 months. Eight of 28 fellow eyes without posterior vitreous detachment and none of 21 fellow eyes with posterior vitreous detachment developed macular holes, suggesting that vitreous attachment to the macula is closely related to the development of macular holes. The difference between the incidences of macular hole development in eyes with and without posterior vitreous detachment is statistically significant.
对126例特发性黄斑裂孔患者的130只眼进行了间接检眼镜、生物显微镜检查、彩色眼底照相及荧光素血管造影检查。这些眼中61%无玻璃体后脱离；78只眼（60%）发现有被解释为盖膜的混浊物。对49只健眼进行了平均47个月的随访。28只无玻璃体后脱离的健眼中有8只发生了黄斑裂孔，而21只伴有玻璃体后脱离的健眼中无一发生黄斑裂孔，这表明玻璃体与黄斑的附着与黄斑裂孔的发生密切相关。有无玻璃体后脱离的眼中黄斑裂孔发生率的差异具有统计学意义。
