Akiba J, Kakehashi A, Arzabe C W, Trempe C L
Schepens Eye Research Institute, Boston, MA 02114.
Ophthalmic Surg. 1992 Sep;23(9):594-7.
The fellow eyes in 84 cases of unilateral idiopathic macular hole were studied retrospectively to determine prognoses and risk factors for this disorder. On initial examination, 15 of 84 eyes (18%) had a macular cystic lesion (group 1), 23 (27%) had a yellow spot in the fovea (group 2), and 46 (55%) had a normal macula (group 3). Of the 84 eyes, 58 (69%) had posterior vitreous attachment. During a mean follow up of 39 months, macular hole developed in 8 of 15 eyes (53%) in group 1, and in 6 of 23 eyes (26%) in group 2. However, a macular hole did not develop in eyes with posterior vitreous separation or a normal macula. Although the risk of developing a macular hole may have been overestimated in our study, posterior vitreous attachment and macular abnormalities may be important in predicting macular hole formation in the fellow eyes in idiopathic macular hole cases.
对84例单侧特发性黄斑裂孔患者的对侧眼进行回顾性研究，以确定该疾病的预后和危险因素。初次检查时，84只眼中有15只（18%）存在黄斑囊性病变（第1组），23只（27%）在黄斑中心凹有黄斑区（第2组），46只（55%）黄斑正常（第3组）。84只眼中有58只（69%）存在玻璃体后脱离。在平均39个月的随访期间，第1组15只眼中有8只（53%）出现黄斑裂孔，第2组23只眼中有6只（26%）出现黄斑裂孔。然而，玻璃体后脱离或黄斑正常的眼未出现黄斑裂孔。尽管在我们的研究中黄斑裂孔发生风险可能被高估，但玻璃体后脱离和黄斑异常可能对预测特发性黄斑裂孔病例对侧眼黄斑裂孔的形成具有重要意义。
