一个关于患者和医生对子宫内膜异位症和瑞戈非尼联合治疗管理的观点的播客。
A Podcast on Patient and Physician Perspectives on the Management of Endometriosis and Relugolix Combination Therapy.
机构信息
Patient Author, The Yellow Cape, Newark, DE, USA.
Center for Endometriosis Research and Treatment, UC San Diego, La Jolla, CA, USA.
出版信息
Adv Ther. 2024 Dec;41(12):4369-4376. doi: 10.1007/s12325-024-02970-2. Epub 2024 Oct 19.
Abstract
Endometriosis is a common disease, affecting approximately 5-10% of reproductively aged women. Symptoms, such as painful periods, negatively impact an individual's quality of life; however, these symptoms are often normalized, leading to delays in diagnosis and treatment, and worsening of the disease. In this podcast, a reproductive endocrinologist (Dr Sanjay K Agarwal) and patient advocate (Tara Mangum) provide their perspectives on the diagnosis and management of endometriosis. They also discuss Relugolix combination therapy as a treatment option for patients with endometriosis.Podcast available for this article.
摘要
子宫内膜异位症是一种常见疾病，影响大约 5-10%的育龄妇女。疼痛等症状会对个人的生活质量产生负面影响；然而，这些症状常常被视为正常，导致诊断和治疗的延误，以及疾病的恶化。在本期播客中，一位生殖内分泌学家（Sanjay K Agarwal 博士）和患者倡导者（Tara Mangum）就子宫内膜异位症的诊断和管理提供了他们的观点。他们还讨论了 Relugolix 联合疗法作为子宫内膜异位症患者的一种治疗选择。本文提供播客。
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本文引用的文献
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Evidence for the role of multidisciplinary team care in people with pelvic pain and endometriosis: A systematic review.多学科团队护理在盆腔疼痛和子宫内膜异位症患者中的作用证据：系统评价。
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Stigma and mental health in endometriosis.子宫内膜异位症中的耻辱感与心理健康
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Evaluation of the effect of previous endometriosis surgery on clinical and surgical outcomes of subsequent endometriosis surgery.评估既往子宫内膜异位症手术对后续子宫内膜异位症手术临床和手术结局的影响。
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Development of relugolix combination therapy as a medical treatment option for women with uterine fibroids or endometriosis.relugolix联合疗法作为子宫肌瘤或子宫内膜异位症女性的一种医学治疗选择的研发。
F S Rep. 2022 Nov 21;4(2 Suppl):73-82. doi: 10.1016/j.xfre.2022.11.010. eCollection 2023 Jun.
5
Once daily oral relugolix combination therapy versus placebo in patients with endometriosis-associated pain: two replicate phase 3, randomised, double-blind, studies (SPIRIT 1 and 2).每日口服瑞戈非尼联合治疗与安慰剂治疗子宫内膜异位症相关疼痛的患者：两项复制的 3 期、随机、双盲、研究（SPIRIT 1 和 2）。
Lancet. 2022 Jun 18;399(10343):2267-2279. doi: 10.1016/S0140-6736(22)00622-5.
6
Lifestyle and Chronic Pain in the Pelvis: State of the Art and Future Directions.骨盆部的生活方式与慢性疼痛：现状与未来方向
J Clin Med. 2021 Nov 19;10(22):5397. doi: 10.3390/jcm10225397.
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Impact of Endometriosis on Life-Course Potential: A Narrative Review.子宫内膜异位症对生命历程潜力的影响：一项叙述性综述。
Int J Gen Med. 2021 Jan 7;14:9-25. doi: 10.2147/IJGM.S261139. eCollection 2021.
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Use of the EFI score in endometriosis-associated infertility: A cost-effectiveness study.子宫内膜异位症相关性不孕中EFI评分的应用：一项成本效益研究。
Eur J Obstet Gynecol Reprod Biol. 2020 Oct;253:296-303. doi: 10.1016/j.ejogrb.2020.08.031. Epub 2020 Aug 27.
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