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探索新型冠状病毒肺炎相关性肠梗阻:一个引人注目的案例研究

Exploring COVID-19-Associated Ileus: A Compelling Case Study.

作者信息

Singh Harpreet, Singh Satnam, Sadhar Birkaran, Winegarden Brad, Morrissey Shawna

机构信息

Medicine, Lake Erie College of Osteopathic Medicine, Erie, USA.

Surgery, Conemaugh Memorial Medical Center, Johnstown, USA.

出版信息

Cureus. 2024 Sep 18;16(9):e69647. doi: 10.7759/cureus.69647. eCollection 2024 Sep.

DOI:10.7759/cureus.69647
PMID:39429337
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11488154/
Abstract

Since the start of 2020, COVID-19 has profoundly impacted global health. Classically, the disease manifests with pulmonary symptoms such as cough, dyspnea, pneumonia, and respiratory distress. However, it is important to note that in addition to these pulmonary symptoms, COVID-19 can present with extrapulmonary symptoms. This case report involves an 82-year-old male who tested positive for the causative agent of COVID-19 - severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), whose presentation manifested with gastrointestinal symptoms in the form of colonic ileus. This report aims to highlight the pathophysiological mechanisms of COVID-19-associated ileus while also delving into the importance of timely intervention to prevent complications like intestinal perforation.

摘要

自2020年初以来,新型冠状病毒肺炎对全球健康产生了深远影响。典型情况下,该疾病表现为咳嗽、呼吸困难、肺炎和呼吸窘迫等肺部症状。然而,需要注意的是,除了这些肺部症状外,新型冠状病毒肺炎还可能出现肺外症状。本病例报告涉及一名82岁男性,他被检测出新型冠状病毒肺炎病原体——严重急性呼吸综合征冠状病毒2(SARS-CoV-2)呈阳性,其表现为以结肠麻痹形式出现的胃肠道症状。本报告旨在强调新型冠状病毒肺炎相关性肠梗阻的病理生理机制,同时深入探讨及时干预以预防肠穿孔等并发症的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1724/11488154/9e64cb7a0191/cureus-0016-00000069647-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1724/11488154/5cc52c6f8101/cureus-0016-00000069647-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1724/11488154/9e64cb7a0191/cureus-0016-00000069647-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1724/11488154/5cc52c6f8101/cureus-0016-00000069647-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1724/11488154/9e64cb7a0191/cureus-0016-00000069647-i04.jpg

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COVID-19: gastrointestinal and hepatobiliary manifestations.新型冠状病毒肺炎:胃肠道和肝胆系统表现。
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Gastrointestinal manifestations in COVID-19.新型冠状病毒肺炎的胃肠道表现。
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Angiotensin-converting enzyme 2 (ACE2), SARS-CoV-2 and the pathophysiology of coronavirus disease 2019 (COVID-19).血管紧张素转化酶 2(ACE2)、严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)与 2019 冠状病毒病(COVID-19)的病理生理学。
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Clinical Characteristics of COVID-19 Patients With Digestive Symptoms in Hubei, China: A Descriptive, Cross-Sectional, Multicenter Study.中国湖北有消化道症状的 COVID-19 患者的临床特征:一项描述性、横断面、多中心研究。
Am J Gastroenterol. 2020 May;115(5):766-773. doi: 10.14309/ajg.0000000000000620.
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Ileus in Adults.成人肠梗阻。
Dtsch Arztebl Int. 2017 Jul 24;114(29-30):508-518. doi: 10.3238/arztebl.2017.0508.