Van Thanh Nguyen, Thi Hoang Lan Vo
Department of Planning and Outreach, Binh Dinh Eye Hospital, Binh Dinh Province, Vietnam.
Department of Ophthalmology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh, Vietnam.
Taiwan J Ophthalmol. 2024 Sep 13;14(3):394-402. doi: 10.4103/tjo.TJO-D-23-00101. eCollection 2024 Jul-Sep.
The objective of this study is to evaluate the sensitivity, specificity, and accuracy of artificial intelligence (AI) for diabetic retinopathy (DR) screening in community in Binh Dinh Province in Vietnam.
This retrospective, descriptive, cross-sectional study assessed the DR screening efficacy of EyeArt system v2.0 by analyzing 2332 nonmydriatic digital fundus pictures of 583 diabetic patients from hospitals and health centers in Binh Dinh province. First, we selected thirty patients with 120 digital fundus pictures to perform the Kappa index by two eye doctors who would be responsible for the DR clinical feature evaluation and DR severity scale classification. Second, all digital fundus pictures were coded and then sent to the two above-mentioned eye doctors for the evaluation and classifications according to the International Committee of Ophthalmology's guidelines. Finally, DR severity scales with EyeArt were compared with those by eye doctors as a reference standard for EyeArt's effectiveness. All the data were analyzed using the SPSS software version 20.0. Values (with confidence interval 95%) of sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were calculated according to DR state, referable or not and vision-threatening DR state or not. < 0.05 was considered statistically significant.
The sensitivity and specificity of EyeArt for DR screening were 94.1% and 87.2%. The sensitivity and specificity for referable DR and vision-threatening DR were 96.6%, 90.1%, and 100.0%, 92.2%. Accuracy for DR screening, referable DR, and vision-threatening DR were 88.9%, 91.4%, and 93.0%, respectively.
EyeArt AI was effective for DR screening in community.
本研究旨在评估人工智能(AI)在越南平定省社区糖尿病视网膜病变(DR)筛查中的敏感性、特异性和准确性。
本回顾性、描述性横断面研究通过分析来自平定省医院和健康中心的583例糖尿病患者的2332张非散瞳数字眼底照片,评估EyeArt系统v2.0的DR筛查效果。首先,我们选取30例患者的120张数字眼底照片,由两名眼科医生进行kappa指数评估,这两名医生负责DR临床特征评估和DR严重程度分级。其次,对所有数字眼底照片进行编码,然后根据国际眼科委员会的指南,将其发送给上述两名眼科医生进行评估和分类。最后,将EyeArt的DR严重程度分级与眼科医生的分级进行比较,以此作为评估EyeArt有效性的参考标准。所有数据均使用SPSS 20.0软件进行分析。根据DR状态(是否为可转诊性DR以及是否为威胁视力的DR状态)计算敏感性、特异性、阳性预测值、阴性预测值和准确性的值(95%置信区间)。P < 0.05被认为具有统计学意义。
EyeArt用于DR筛查的敏感性和特异性分别为94.1%和87.2%。对于可转诊性DR和威胁视力的DR,其敏感性和特异性分别为96.6%、90.1%以及100.0%、92.2%。DR筛查、可转诊性DR和威胁视力的DR的准确性分别为88.9%、91.4%和93.0%。
EyeArt人工智能在社区DR筛查中有效。