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基于人工智能的社区医院糖尿病视网膜病变筛查。

Artificial intelligence-based screening for diabetic retinopathy at community hospital.

机构信息

Department of Ophthalmology, Shanghai Shibei Hospital of Jing'an District, Shanghai, China.

Community Health Service Center, PengPu Town, Jing'an District, Shanghai, China.

出版信息

Eye (Lond). 2020 Mar;34(3):572-576. doi: 10.1038/s41433-019-0562-4. Epub 2019 Aug 27.

DOI:10.1038/s41433-019-0562-4
PMID:31455902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7042314/
Abstract

OBJECTIVES

The purpose of this study is to assess the accuracy of artificial intelligence (AI)-based screening for diabetic retinopathy (DR) and to explore the feasibility of applying AI-based technique to community hospital for DR screening.

METHODS

Nonmydriatic fundus photos were taken for 889 diabetic patients who were screened in community hospital clinic. According to DR international classification standards, ophthalmologists and AI identified and classified these fundus photos. The sensitivity and specificity of AI automatic grading were evaluated according to ophthalmologists' grading.

RESULTS

DR was detected by ophthalmologists in 143 (16.1%) participants and by AI in 145 (16.3%) participants. Among them, there were 101 (11.4%) participants diagnosed with referable diabetic retinopathy (RDR) by ophthalmologists and 103 (11.6%) by AI. The sensitivity, specificity and area under the curve (AUC) of AI for detecting DR were 90.79% (95% CI 86.4-94.1), 98.5% (95% CI 97.8-99.0) and 0.946 (95% CI 0.935-0.956), respectively. For detecting RDR, the sensitivity, specificity and AUC of AI were 91.18% (95% CI 86.4-94.7), 98.79% (95% CI 98.1-99.3) and 0.950 (95% CI 0.939-0.960), respectively.

CONCLUSION

AI has high sensitivity and specificity in detecting DR and RDR, so it is feasible to carry out AI-based DR screening in outpatient clinic of community hospital.

摘要

目的

本研究旨在评估基于人工智能(AI)的糖尿病视网膜病变(DR)筛查的准确性,并探讨将基于 AI 的技术应用于社区医院进行 DR 筛查的可行性。

方法

对在社区医院诊所接受筛查的 889 例糖尿病患者进行免散瞳眼底照相。根据 DR 国际分类标准,由眼科医生和 AI 对这些眼底照片进行识别和分类。根据眼科医生的分级,评估 AI 自动分级的敏感性和特异性。

结果

眼科医生在 143 名(16.1%)参与者中检测到 DR,AI 在 145 名(16.3%)参与者中检测到 DR。其中,有 101 名(11.4%)参与者被眼科医生诊断为有意义的糖尿病性视网膜病变(RDR),有 103 名(11.6%)参与者被 AI 诊断为 RDR。AI 检测 DR 的敏感性、特异性和曲线下面积(AUC)分别为 90.79%(95%CI 86.4-94.1)、98.5%(95%CI 97.8-99.0)和 0.946(95%CI 0.935-0.956)。对于检测 RDR,AI 的敏感性、特异性和 AUC 分别为 91.18%(95%CI 86.4-94.7)、98.79%(95%CI 98.1-99.3)和 0.950(95%CI 0.939-0.960)。

结论

AI 在检测 DR 和 RDR 方面具有较高的敏感性和特异性,因此在社区医院门诊进行基于 AI 的 DR 筛查是可行的。