Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, China.
Front Public Health. 2024 Oct 4;12:1415833. doi: 10.3389/fpubh.2024.1415833. eCollection 2024.
The objective of this study was to investigate the prevalence of overactive bladder (OAB) and its risk factors related to allergies among children in Northeastern China.
A community survey on OAB was conducted in Northeast China from 1 April 2022 to 30 April 2022. The survey targeted children aged 5-14 years and utilized questionnaires. A total of 1,394 children were enrolled, and their parents were requested to fill out a questionnaire to provide basic information about the children. This encompassed details regarding the presence or absence of urgent urination unrelated to urinary tract infection, urinary tract infection, allergic rhinitis, asthma or cough variant asthma, atopic dermatitis, anaphylactic conjunctivitis, urticaria, constipation, and attention deficit hyperactivity disorder (ADHD). The prevalence of OAB was calculated. The chi-squared test was used to analyze OAB-related factors, which were subsequently included in the logistic regression model for multi-factor analysis.
The overall OAB prevalence was 10.7% (120 of 1,121), including 47 mild cases (39.2%), 71 moderate cases (59.1%), and 2 severe cases (1.7%). OAB prevalence decreased with age ( < 0.05). The risk factors associated with OAB were allergic asthma (OR = 1.87, 95%CI: 1.12-3.13), atopic dermatitis (OR = 2.45, 95%CI: 1.61-3.73), anaphylactic conjunctivitis (OR = 1.61, 95%CI: 1.07-2.42), and urticaria (OR = 1.93, 95%CI: 1.40-2.66).
OAB prevalence among children in Northeastern China was found to be 10.7%, with its risk factors being allergic asthma, anaphylactic conjunctivitis, urticaria, and atopic dermatitis. The identification of allergy-related risk factors may provide new ideas for the prevention and treatment of OAB.
本研究旨在调查中国东北地区儿童中过度膀胱活动症（OAB）的患病率及其与过敏相关的危险因素。
2022 年 4 月 1 日至 4 月 30 日，在中国东北地区进行了一项关于 OAB 的社区调查。该调查针对 5-14 岁的儿童，采用问卷形式。共纳入 1394 名儿童，其父母被要求填写一份问卷，提供有关儿童的基本信息。其中包括有无与尿路感染无关的急迫性尿失禁、尿路感染、变应性鼻炎、哮喘或咳嗽变异性哮喘、特应性皮炎、过敏性结膜炎、荨麻疹、便秘和注意缺陷多动障碍（ADHD）等信息。计算 OAB 的患病率。采用卡方检验分析 OAB 相关因素，然后将其纳入多因素 logistic 回归模型进行分析。
总体 OAB 患病率为 10.7%（120/1121），其中轻度 47 例（39.2%），中度 71 例（59.1%），重度 2 例（1.7%）。OAB 患病率随年龄增长而降低（ < 0.05）。与 OAB 相关的危险因素包括过敏性哮喘（OR=1.87，95%CI：1.12-3.13）、特应性皮炎（OR=2.45，95%CI：1.61-3.73）、过敏性结膜炎（OR=1.61，95%CI：1.07-2.42）和荨麻疹（OR=1.93，95%CI：1.40-2.66）。
中国东北地区儿童 OAB 患病率为 10.7%，其危险因素为过敏性哮喘、过敏性结膜炎、荨麻疹和特应性皮炎。识别与过敏相关的危险因素可能为 OAB 的预防和治疗提供新的思路。
