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非侵入性脑刺激技术治疗尼古丁成瘾的疗效与安全性:随机对照试验的系统评价

Efficacy and safety of non-invasive brain stimulation techniques for the treatment of nicotine addiction: A systematic review of randomized controlled trials.

作者信息

Iannuzzo Fiammetta, Crudo Silvia, Basile Gianpaolo Antonio, Battaglia Fortunato, Infortuna Carmenrita, Muscatello Maria Rosaria Anna, Bruno Antonio

机构信息

Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Via Consolare Valeria 1, Contesse, Messina 98125, Italy.

Department of Medical Sciences, Neurology and Psychiatry, Hackensack Meridian School of Medicine, Nutley, NJ 07110, USA.

出版信息

AIMS Neurosci. 2024 Jul 1;11(3):212-225. doi: 10.3934/Neuroscience.2024014. eCollection 2024.

DOI:10.3934/Neuroscience.2024014
PMID:39431276
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11486613/
Abstract

Non-Invasive Brain Stimulation (NIBS) techniques seem to be effective in treating tobacco use disorder. We aimed to analyze what kinds of protocols are used to treat nicotine addiction in term of cessation and/or reduction and to evaluate the long-term effects of NIBS techniques. We searched PubMed, Scopus, and Web of Science for papers published, with combinations of the following search terms: "". We conducted a preliminary search, which revealed papers on the topic. Articles were included in the review according to the following inclusion criteria: English language, publication in peer reviewed journals, articles about studies performed on non-invasive brain stimulations techniques, and RCT studies. Studies involving clinical populations with organic or psychiatric diseases were excluded. We found 280 articles. Of these, at the first screening and conducted by title and abstract, 63 studies were excluded after duplicates were removed (118). After the second screening conducted by full-text examination, 45 articles were excluded. Ten studies met the inclusion criteria and were included in the review. The clinical benefits of NIBS, including the fast onset and minor side effects, showed that this kind of treatment could be helpful in patients with a long history of smoking in terms of cessation and abstinence rates.

摘要

非侵入性脑刺激(NIBS)技术似乎在治疗烟草使用障碍方面有效。我们旨在分析在戒烟和/或减少吸烟方面用于治疗尼古丁成瘾的各种方案,并评估NIBS技术的长期效果。我们在PubMed、Scopus和科学网中搜索已发表的论文,使用以下搜索词组合:“”。我们进行了初步搜索,发现了关于该主题的论文。根据以下纳入标准,文章被纳入综述:英文、发表在同行评审期刊上、关于非侵入性脑刺激技术研究的文章以及随机对照试验研究。涉及患有器质性或精神疾病临床人群的研究被排除。我们找到了280篇文章。其中,在首次通过标题和摘要进行筛选时,去除重复项后排除了63项研究(共118项)。在通过全文检查进行第二次筛选后,又排除了45篇文章。十项研究符合纳入标准并被纳入综述。NIBS的临床益处,包括起效快和副作用小,表明这种治疗对于有长期吸烟史的患者在戒烟率和戒断率方面可能有帮助。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2468/11486613/bb7dc4b5f8f7/neurosci-11-03-014-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2468/11486613/bb7dc4b5f8f7/neurosci-11-03-014-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2468/11486613/bb7dc4b5f8f7/neurosci-11-03-014-g001.jpg

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本文引用的文献

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Non-invasive brain stimulation for patients and healthy subjects: Current challenges and future perspectives.非侵入性脑刺激在患者和健康受试者中的应用:当前挑战与未来展望。
J Neurol Sci. 2024 Jan 15;456:122825. doi: 10.1016/j.jns.2023.122825. Epub 2023 Dec 10.
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Efficacy of insula deep repetitive transcranial magnetic stimulation combined with varenicline for smoking cessation: A randomized, double-blind, sham controlled trial.
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Safety Review for Clinical Application of Repetitive Transcranial Magnetic Stimulation.重复经颅磁刺激临床应用的安全性综述
Brain Neurorehabil. 2021 Mar 18;14(1):e6. doi: 10.12786/bn.2021.14.e6. eCollection 2021 Mar.
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