R Adams Cowley Shock Trauma, The University of Maryland School of Medicine, Baltimore, MD, USA.
Adv Neurobiol. 2024;42:99-118. doi: 10.1007/978-3-031-69832-3_5.
Traumatic brain injuries are increasingly common in older adults and represent a substantial source of morbidity and mortality for this population. In addition to the impact from the primary insult, TBI can lead to a variety of chronic neurocognitive conditions including dementia, depression, and sleep disturbances. When caused by TBI, these conditions differ importantly from their non-TBI-related counterparts. Much about how TBI relates to the development of these conditions is unknown, and more research is needed to further elucidate optimal treatment strategies.
创伤性脑损伤在老年人中越来越常见，是该人群发病率和死亡率的一个重要来源。除了原发性损伤的影响外，TBI 还可导致多种慢性神经认知疾病，包括痴呆、抑郁和睡眠障碍。当由 TBI 引起时，这些疾病与非 TBI 相关疾病有很大的不同。TBI 与这些疾病发展的关系有很多尚不清楚，需要更多的研究来进一步阐明最佳治疗策略。
