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巴基斯坦结核病疫情上升:因素、影响及多方面的预防和控制方法。

The rising tide of tuberculosis in Pakistan: Factors, impact, and multi-faceted approaches for prevention and control.

作者信息

Ullah Hamid, Ahmed Hafsa, Salman Ariba, Iqbal Rabia, Hussaini Sayed Jawad, Malikzai Abdullah

机构信息

Faculty of Medicine, Dow Medical College Dow University of Health and Sciences Karachi Pakistan.

Faculty of Medical Technology Dow University of Health Sciences Karachi Pakistan.

出版信息

Health Sci Rep. 2024 Oct 20;7(10):e70130. doi: 10.1002/hsr2.70130. eCollection 2024 Oct.

Abstract

BACKGROUND

Tuberculosis (TB) remains a major public health concern in Pakistan, which is ranked fifth among high-burden TB nations worldwide. The growing frequency of drug-resistant TB strains, particularly multidrug-resistant TB (MDR-TB), creates new obstacles. Socioeconomic factors, a lack of awareness, and inadequate healthcare infrastructure all contribute to the spread of the disease.

OBJECTIVE

This study investigates the mechanisms contributing to the growth in tuberculosis cases in Pakistan, the implications for public health, and multifaceted approaches to prevention and control.

METHODS

A comprehensive literature study was undertaken, including an analysis of peer-reviewed articles, World Health Organization (WHO) data, and government sources, to identify factors driving tuberculosis prevalence, control issues, and disease-fighting tactics.Result: Several factors like Poverty, overcrowding, malnutrition, stigma, and restricted access to healthcare services are all factors contributing to an increase in tuberculosis incidence in Pakistan. The prevalence of MDR-TB, along with a lack of an integrated healthcare response, complicates efforts to contain the disease's spread. Tuberculosis has a profound social, mental, and financial impact on individuals and communities. Public health efforts, such as the National Tuberculosis Control Program (NTP) and international partnerships, have been created to eradicate tuberculosis, although considerable hurdles persist.

OBJECTIVE

This study investigates the mechanisms contributing to the growth in tuberculosis cases in Pakistan, the implications for public health, and multifaceted approaches to prevention and control.

摘要

背景

结核病仍然是巴基斯坦主要的公共卫生问题,该国在全球结核病高负担国家中排名第五。耐药结核菌株,特别是耐多药结核病(MDR-TB)的日益频繁出现带来了新的障碍。社会经济因素、意识缺乏和医疗基础设施不足都促使了该疾病的传播。

目的

本研究调查了导致巴基斯坦结核病病例增加的机制、对公共卫生的影响以及多方面的预防和控制方法。

方法

进行了一项全面的文献研究,包括对同行评审文章、世界卫生组织(WHO)数据和政府来源的分析,以确定推动结核病流行的因素、控制问题和抗病策略。结果:贫困、过度拥挤、营养不良、耻辱感以及获得医疗服务的机会有限等几个因素都是导致巴基斯坦结核病发病率上升的因素。耐多药结核病的流行,加上缺乏综合医疗应对措施,使控制该疾病传播的努力变得复杂。结核病对个人和社区有着深远的社会、心理和经济影响。为了根除结核病,已经开展了诸如国家结核病控制计划(NTP)和国际伙伴关系等公共卫生努力,尽管仍然存在相当大的障碍。

目的

本研究调查了导致巴基斯坦结核病病例增加的机制、对公共卫生的影响以及多方面的预防和控制方法。

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本文引用的文献

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MDR-TB in Pakistan: Challenges, efforts, and recommendations.巴基斯坦的耐多药结核病:挑战、努力及建议
Ann Med Surg (Lond). 2022 Jun 17;79:104009. doi: 10.1016/j.amsu.2022.104009. eCollection 2022 Jul.
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Inadequate housing and pulmonary tuberculosis: a systematic review.住房不足与肺结核:系统评价。
BMC Public Health. 2022 Mar 30;22(1):622. doi: 10.1186/s12889-022-12879-6.

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