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一名老年患者因伤口被土壤污染后发生撕裂伤,继而出现全身性破伤风并合并Takotsubo心肌病——病例报告

Generalized tetanus complicated with Takotsubo-cardiomyopathy in a septuagenarian following a laceration injury with soil contamination - a case report.

作者信息

Bandapaati Sareesh, Mitrakrishnan Rayno Navinan, Islam Mazharul, Memon Usman

机构信息

Kettering General Hospital, NHS, Kettering, UK.

University Hospital - Kotelawala Defence University, Colombo, Sri Lanka.

出版信息

Int J Emerg Med. 2024 Oct 22;17(1):162. doi: 10.1186/s12245-024-00751-w.

Abstract

BACKGROUND

Tetanus is a clinical rarity due to the successful globally adopted childhood vaccination programme. The rising elderly population in the United Kingdom creates a subset of individuals whom are prone to develop Tetanus as they preceded this vaccination drive. A 76 year old Caucasian lady presented with a soil contaminated laceration injury on her knee following a fall. Though she received urgent assessment and wound care, the relevance of the injury in the backdrop of her age was not appreciated and her tetanus post exposure prophylaxis was overlooked. She readmitted seeking further management 1 week later with an infected wound with Trismus and clinical features favoring Generalized tetanus. During her stay she developed Takotsubo-cardiomyopathy with congestive cardiac failure and required prolonged care in the intensive unit with mechanical ventilation and rehabilitation before being discharged home.

CONCLUSION

First contact physicians should have a greater appreciation of the types of injuries and at-risk individuals who are more prone to develop tetanus upon exposure to ensure early and appropriate identification. There should be greater situational awareness with regard to the elderly in view of their heightened risk of development of tetanus specially those born before the vaccination drive. Knowledge regarding post exposure prophylaxis measures for tetanus should be regularly updated using local guidance to ensure awareness, so as to despite its rarity Tetanus remains an adequately appreciated disease.

摘要

背景

由于全球成功推行儿童疫苗接种计划,破伤风在临床上已较为罕见。英国老年人口不断增加,形成了一部分在疫苗接种运动之前出生的、容易感染破伤风的人群。一名76岁的白种女性在跌倒后膝盖被土壤污染造成撕裂伤。尽管她接受了紧急评估和伤口护理,但由于她的年龄,此次受伤的相关性未得到重视,她的破伤风暴露后预防措施也被忽视了。1周后,她因伤口感染、牙关紧闭以及具有全身性破伤风的临床特征而再次入院寻求进一步治疗。住院期间,她发展为应激性心肌病并伴有充血性心力衰竭,在重症监护室需要长时间的护理,包括机械通气和康复治疗,之后才出院回家。

结论

首诊医生应更深入了解受伤类型以及暴露后更易感染破伤风的高危个体,以确保早期和恰当的识别。鉴于老年人感染破伤风的风险增加,尤其是那些在疫苗接种运动之前出生的老年人,应对此有更高的情境意识。应根据当地指南定期更新破伤风暴露后预防措施的知识,以确保医护人员了解,从而尽管破伤风较为罕见,但仍是一种得到充分认识的疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e25e/11520159/021d8e6e16ad/12245_2024_751_Figa_HTML.jpg

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