Brandsæter Bjørn, Aaberge Ingeborg S, Dunlop Oona
Department of Infectious Diseases, Oslo University Hospital Ullevaal, Norway.
Norwegian Institute of Public Health, Division of Infectious Disease Control, Oslo, Norway.
IDCases. 2015 Apr 2;2(2):53-5. doi: 10.1016/j.idcr.2015.03.003. eCollection 2015.
Tetanus vaccination is part of the Norwegian childhood vaccination program. An elderly woman injured her arm and leg after a minor fall on her outdoor stairs. Two weeks later she presented with trismus. This developed into tetanic spasms, obstructed airways and the need for a tracheostomy. She died 14 days later due to pneumonia and multi-organ failure. ELISA for tetanus toxoid IgG was negative, probably because the patient was born before the introduction of tetanus vaccination in the Norwegian childhood vaccination program. Lack of adherence to the vaccination programs should be considered in patients presenting with symptoms resembling diseases they normally would be protected from. Although the patient presented with typical symptoms the diagnosis was not suspected initially, probably due to the rareness of this disease in Norway.
破伤风疫苗接种是挪威儿童疫苗接种计划的一部分。一名老年女性在户外楼梯上轻微摔倒后,手臂和腿部受伤。两周后,她出现牙关紧闭症状。这发展为破伤风痉挛、气道阻塞,需要进行气管切开术。14天后,她因肺炎和多器官衰竭死亡。破伤风类毒素IgG的酶联免疫吸附测定(ELISA)结果为阴性,可能是因为该患者出生于挪威儿童疫苗接种计划引入破伤风疫苗之前。对于出现类似他们通常应受保护疾病症状的患者,应考虑未遵守疫苗接种计划的情况。尽管该患者出现了典型症状,但最初并未怀疑诊断,可能是由于这种疾病在挪威较为罕见。