Williamson Grace, Trompeter Nora, Murphy Dominic, Saba Shaddy, Pedersen Eric R, Davis Jordan P, Leightley Daniel
King's Centre for Military Health Research, Institute of Psychiatry, Psychology & Neuroscience, King's College London, United Kingdom.
King's Centre for Military Health Research, Institute of Psychiatry, Psychology & Neuroscience, King's College London, United Kingdom, and, Combat Stress, Leatherhead, United Kingdom.
Mental Health Sci. 2024 Sep;2(3). doi: 10.1002/mhs2.75. Epub 2024 Jun 23.
Post-traumatic stress disorder (PTSD) and comorbid cannabis use disorder (CUD) is a growing concern amongst UK veterans. Co-occurrence of problematic cannabis use, and PTSD is associated with greater PTSD symptom severity, decreased likelihood of cannabis use cessation, worse clinical outcomes, and increased societal burden. Despite increased screening efforts among veterans, there are no effective strategies for predicting risk for PTSD and problematic drug use escalation before these conditions develop, worsen, or become chronic.
This feasibility study employs a 4-week (28 day) longitudinal design (daily data collection), multiple passive data collection features via a bespoke study smartphone app called MAVERICK, and active data collection via wearable technology to predict clinically meaningful escalations in cannabis use and PTSD symptoms in UK veterans. Questionnaire data will be collected between 06:00 and 10:00 each day. Passive data will be collected continuously in the background.
The study will begin recruitment in June 2023 and will require 18 months to complete. Study results are expected to be published in January 2024.
This trial will provide information on the feasibility and utility of a smartphone app (MAVERICK) to collect both active and passive data to predict PTSD symptoms and cannabis use in a UK veteran population. If the smartphone app is deemed feasible and acceptable to users, it has the potential to provide an effective measurement tool to mitigate risk of PTSD and problematic cannabis use among veterans.
创伤后应激障碍（PTSD）与共病的大麻使用障碍（CUD）在英国退伍军人中日益受到关注。大麻使用问题与创伤后应激障碍同时出现，与创伤后应激障碍症状严重程度增加、大麻使用戒断可能性降低、临床结果更差以及社会负担加重有关。尽管退伍军人中的筛查工作有所增加，但在这些情况发展、恶化或变为慢性之前，尚无有效的策略来预测创伤后应激障碍和药物使用问题升级的风险。
这项可行性研究采用为期4周（28天）的纵向设计（每日数据收集），通过一款名为MAVERICK的定制研究智能手机应用程序进行多种被动数据收集功能，并通过可穿戴技术进行主动数据收集，以预测英国退伍军人中大麻使用和创伤后应激障碍症状具有临床意义的升级情况。问卷数据将在每天06:00至10:00之间收集。被动数据将在后台持续收集。
该研究将于2023年6月开始招募，需要18个月完成。研究结果预计于2024年1月发表。
该试验将提供有关智能手机应用程序（MAVERICK）收集主动和被动数据以预测英国退伍军人创伤后应激障碍症状和大麻使用的可行性和实用性的信息。如果该智能手机应用程序被认为对用户可行且可接受，它有可能提供一种有效的测量工具，以降低退伍军人中创伤后应激障碍和大麻使用问题的风险。
