Key Laboratory of Functional Inorganic Material Chemistry, School of Chemistry and Materials Science, Ministry of Education, Heilongjiang University, Harbin, 150080, China.
Mikrochim Acta. 2024 Oct 23;191(11):694. doi: 10.1007/s00604-024-06731-4.
Public health and environmental well-being have become increasingly threatened by the contamination of pharmaceuticals and heavy metal ions. This study focuses on addressing this critical issue by developing a novel electrochemical sensor for the dual-functional detection of acetaminophen (AP) and Cu. Utilizing willow catkins as a biomass template, a hollow tubular NiS@NSC composite was prepared by simple nickel salt impregnation combined with calcination and sulfurization. A highly sensitive dual-functional electrochemical sensor was thus constructed that can detect both acetaminophen (AP) and Cu. By examining its electrochemical properties, the sensor achieves an impressive detection limit of 1.33 pM for AP, with a linear range of 4.00 pM ~ 0.15 mM. The sensor can also detect Cu, with a detection limit of 1.04 µM, and a linear range of 3.13 µM ~ 0.66 mM. The sensor also exhibits strong resistance to interference, and good repeatability and stability. In addition, the sensor has demonstrated good performance in actual sample analysis, including the detection of AP in serum and Cu in wastewater. This excellent electrochemical sensing performance is mainly attributed to the synergistic effect of its unique tubular structure and highly conductive N, S co-doped carbon. This results in the sensor exhibiting minimal charge transfer resistance, an extensive electrochemically active surface area, and a high density of active sites.
公众健康和环境福祉受到药品和重金属离子污染的威胁日益严重。本研究通过开发一种新型电化学传感器，用于同时检测扑热息痛（AP）和 Cu，聚焦解决这一关键问题。利用柳絮作为生物质模板，通过简单的镍盐浸渍结合煅烧和硫化制备了空心管状 NiS@NSC 复合材料。构建了一种高灵敏度的双功能电化学传感器，可同时检测扑热息痛（AP）和 Cu。通过检查其电化学性质，该传感器对 AP 的检测限达到了 1.33 pM，线性范围为 4.00 pM 至 0.15 mM。该传感器还可以检测 Cu，检测限为 1.04 µM，线性范围为 3.13 µM 至 0.66 mM。该传感器还表现出对干扰的强抵抗力，以及良好的重复性和稳定性。此外，该传感器在实际样品分析中表现出良好的性能，包括对血清中的 AP 和废水中的 Cu 的检测。这种优异的电化学传感性能主要归因于其独特的管状结构和高导电性 N、S 共掺杂碳的协同效应。这导致传感器表现出最小的电荷转移电阻、广泛的电化学活性表面积和高密度的活性位点。
