Departamento de Enfermería, Facultad de Medicina y Ciencias de la Salud, Universidad de Extremadura, 06006 Badajoz, Spain.
Hospital Universitario de Badajoz, 06006 Badajoz, Spain.
Int J Environ Res Public Health. 2022 Mar 16;19(6):3547. doi: 10.3390/ijerph19063547.
Breast cancer (BC) is a major public health problem internationally. Although illness survival rates have improved, patients usually suffer multiple symptoms, both physical and psychological, which can affect their quality of life (QoL). The main aim of this study was to evaluate depressive symptoms, anxiety and the QoL of people with BC. An observational, cross-sectional study was carried out at Badajoz University Hospital (Spain). A total of 200 women with BC were included. EORTC QLQ-C30 and QLQ-BR23 questionnaires were used to assess QoL. Patients were screened for depressive symptoms using the Beck Depression Inventory (BDI) and for state anxiety and trait anxiety using the State Anxiety Inventory (STAI). Thirty-eight percent of the patients in the sample had moderate to severe anxiety, which was related to the time of diagnosis, advanced stage of illness and surgical treatment. We found that 28% of patients had depressive symptoms, related mainly with time of diagnosis, adjuvant therapy and number of cycles of chemotherapy (CT). Patients with the longest time since diagnosis, in stage III, and in treatment with CT, especially those with the greatest number of cycles, had the worst scores in QoL. We found a positive association between depressive symptoms and anxiety with QoL in patients with BC.
乳腺癌（BC）是一个国际性的主要公共卫生问题。尽管疾病存活率有所提高，但患者通常会出现多种身体和心理症状，这会影响他们的生活质量（QoL）。本研究的主要目的是评估乳腺癌患者的抑郁症状、焦虑和生活质量。这是一项在巴达霍斯大学医院（西班牙）进行的观察性、横断面研究。共纳入 200 名乳腺癌患者。使用 EORTC QLQ-C30 和 QLQ-BR23 问卷评估 QoL。使用贝克抑郁量表（BDI）筛查患者的抑郁症状，使用状态焦虑量表（STAI）筛查患者的状态焦虑和特质焦虑。样本中 38%的患者有中度至重度焦虑，这与诊断时间、疾病晚期和手术治疗有关。我们发现 28%的患者有抑郁症状，主要与诊断时间、辅助治疗和化疗（CT）周期数有关。诊断时间最长、处于 III 期和接受 CT 治疗的患者，尤其是接受最多周期 CT 治疗的患者，其 QoL 评分最差。我们发现乳腺癌患者的抑郁症状和焦虑与 QoL 呈正相关。
