College of Chemistry and Chemical Engineering, Xi'an Shiyou University, Xi'an 710065, China.
Beijing National Laboratory for Molecular Sciences, CAS Key Lab of Colloid, Interface and Chemical Thermodynamics, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Adv Colloid Interface Sci. 2024 Dec;334:103316. doi: 10.1016/j.cis.2024.103316. Epub 2024 Oct 15.
Polydopamine (PDA)-based materials inspired by the adhesive proteins of mussels have attracted increasing attention owing to the universal adhesiveness, antioxidant activity, fluorescence quenching ability, excellent biocompatibility, and especially photothermal conversion capability. The high binding ability of PDA to a variety of metal ions offers a paradigm for the exploration of metal-chelated polydopamine nanomaterials with fantastic properties and functions. This review systematically summarizes the latest progress of metal-chelated polydopamine nanomaterials for the applications in biomedicine, catalysis, and energy storage. Different fabrication strategies for metal-chelated polydopamine nanomaterials with various composition, structure, size, and surface chemistry, such as the pre-functionalization method, the one-pot co-assembly method, and the post-modification method, are summarized. Furthermore, emerging applications of metal-chelated polydopamine nanomaterials in the fields ranging from cancer therapy, theranostics, antibacterial, catalysis to energy storage are highlighted. Additionally, the critical remaining challenges and future directions of this area are discussed to promote the further development and practical applications of PDA-based materials.
基于贻贝类黏附蛋白的聚多巴胺（PDA）材料因其普遍的黏附性、抗氧化活性、荧光猝灭能力、良好的生物相容性和出色的光热转换能力而受到越来越多的关注。PDA 与多种金属离子的高结合能力为探索具有奇异性能和功能的金属螯合聚多巴胺纳米材料提供了范例。本综述系统地总结了金属螯合聚多巴胺纳米材料在生物医学、催化和储能方面的最新进展。综述了不同的金属螯合聚多巴胺纳米材料的制备策略，包括预功能化方法、一锅共组装方法和后修饰方法，这些方法具有不同的组成、结构、尺寸和表面化学性质。此外，还强调了金属螯合聚多巴胺纳米材料在癌症治疗、治疗学、抗菌、催化和储能等领域的新兴应用。此外，还讨论了该领域的关键剩余挑战和未来方向，以促进基于 PDA 的材料的进一步发展和实际应用。
