Yin Xi, Huang Shengyu, Zhu Zhihao, Ma Qimin, Wang Yusong, Liu Xiaobin, Shen Tuo, Zhu Feng
Department of Burns and Plastic Surgery, Zhangjiagang Hospital affiliated to Soochow University, Suzhou, 215600, Jiangsu Province, China.
Medical Center of Burn plastic and wound repair, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, Jiangxi Province, China.
Injury. 2025 Jan;56(1):111955. doi: 10.1016/j.injury.2024.111955. Epub 2024 Oct 15.
Burn caused by exposure to hot substances is a common occurrence but there is little data on prevalence trends and disease burden. This research report the burden of burn injuries globally, regionally, and nationally from 1990 to 2019, identify hotspots, and analyze factors affecting disease burden with data from Global Burden of Disease 2019 survey.
The Global Burden of Disease 2019 estimated the incidence, death rate, and disease-adjusted life years (DALY) for injuries due to exposure to fire, heat, and hot substances from 1990 to 2019. For comparison, all rates were age standardized. And the estimated annual percentage change (EAPC) was used to reflect the degree of change of the annual rate.
Globally, there were an estimated 8,378,122 (95 % uncertainty interval [UI]: 6,531,887-10,363,109) burn injuries in 2019, with age-standardized incidence, death, and DALY rates of 118 (95 % UI: 89-147), 1.44 (95 % UI: 1.14-1.72), and 96.6 (95 % UI: 75.03-123.05) per 100,000 people, which were 22 %, 43 %, and 43 % lower than those in 1990, respectively. Regionally, age-standardized incidence rate showed a positive association with Socio-demographic Index (SDI) from 1990 to 2019, whereas age-standardized death and DALY rates were negatively associated with SDI. The variation in the age-standardized incidence rate was intrinsic, and the variation in the age-standardized death rate was related to the human development index in the country. The global burn incidence population was skewed, with peaks mainly in the 5 to 19 years age group, but age-specific death rates and disease burden were higher in the under-5 and older age groups.
The results of this study indicate the need to consider regional differences in burns when allocating health resources. Despite the reduced global burden of burns, incidence and deaths remain high. Moreover, there are significant differences between regions which are associated with the SDI and the human development index. Additionally, differences exist in the age and sex of the affected populations. Although the exact causes require further study, there is no doubt that the prevention of burns requires serious attention.
接触热物质导致的烧伤很常见,但关于患病率趋势和疾病负担的数据很少。本研究报告了1990年至2019年全球、区域和国家层面的烧伤负担,确定了热点地区,并利用2019年全球疾病负担调查的数据分析了影响疾病负担的因素。
《2019年全球疾病负担》估计了1990年至2019年因接触火灾、热和热物质导致的伤害的发病率、死亡率和伤残调整生命年(DALY)。为了进行比较,所有率都进行了年龄标准化。并使用估计的年度百分比变化(EAPC)来反映年率的变化程度。
2019年全球估计有8378122例(95%不确定区间[UI]:6531887 - 10363109)烧伤,年龄标准化发病率、死亡率和DALY率分别为每10万人118例(95% UI:89 - 147)、1.44例(95% UI:1.14 - 1.72)和96.6例(95% UI:75.03 - 123.05),分别比1990年低22%、43%和43%。在区域层面,1990年至2019年年龄标准化发病率与社会人口指数(SDI)呈正相关,而年龄标准化死亡率和DALY率与SDI呈负相关。年龄标准化发病率的变化是内在的,年龄标准化死亡率的变化与国家的人类发展指数有关。全球烧伤发病人口分布不均衡,高峰主要在5至19岁年龄组,但5岁以下和老年组的年龄特异性死亡率和疾病负担更高。
本研究结果表明,在分配卫生资源时需要考虑烧伤的区域差异。尽管全球烧伤负担有所减轻,但发病率和死亡率仍然很高。此外,各区域之间存在显著差异,这与SDI和人类发展指数有关。此外,受影响人群在年龄和性别上也存在差异。虽然确切原因需要进一步研究,但毫无疑问,烧伤预防需要得到认真关注。