Division of Acute Care Surgery, Department of Surgery, Korea University Anam Hospital, Korea University School of Medicine, Seoul, South Korea.
Department of Internal Medicine, Chungnam University Sejong Hospital, Chungnam National University College of Medicine, Sejong-si, South Korea.
Sci Rep. 2024 Oct 24;14(1):25115. doi: 10.1038/s41598-024-76038-0.
Background This study aimed to determine the proportion of organ donors suitable for donation after circulatory death and investigate the current process followed by critical care physicians for declaring circulatory death to establish organ donation. Methods This observational study involved potential organ donors who had recently died after discontinuation of life support. We conducted an online survey of intensivists to determine how these deaths were confirmed. Results Among the 177 patients who died after withdrawal of life-sustaining treatment across 19 intensive care units in 11 institutions, 49 (27.7%) were considered potential donors. According to general medical criteria for organ donation, 20 (11.3%) patients were identified as medically suitable donors. Notably, 116 (73.9%) patients exhibited a flat electrocardiogram within 5 min after the loss of pulse. In the survey, 90 physicians (59.2%) agreed to implement the concept of the 5-min no-touch period for the declaration of circulatory death. Conclusions This study found that 11.3% of the patients who died following the withdrawal of life-sustaining treatment in the intensive care units were identified as suitable donors after circulatory death. Most of critical care physicians agree with the concept of a 5-min no-touch period for the declaration of circulatory death.
背景 本研究旨在确定适合在循环死亡后捐献器官的供体比例,并调查重症监护医师目前宣布循环死亡以建立器官捐献的流程。
方法 这是一项观察性研究,涉及最近在停止生命支持后死亡的潜在器官捐献者。我们对重症监护医师进行了在线调查,以确定如何确认这些死亡。
结果 在 11 家机构的 19 个重症监护病房中,有 177 名患者在停止生命支持治疗后死亡,其中 49 名(27.7%)被认为是潜在的供体。根据器官捐献的一般医学标准,20 名(11.3%)患者被确定为医学上合适的供体。值得注意的是,116 名(73.9%)患者在脉搏丧失后 5 分钟内心电图呈平线。在调查中,90 名医生(59.2%)同意实施循环死亡宣告的 5 分钟无接触期概念。
结论 本研究发现,在重症监护病房停止生命支持治疗后死亡的患者中,11.3%被确定为循环死亡后的适合捐献者。大多数重症监护医师同意循环死亡宣告的 5 分钟无接触期概念。