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HIV 同伴支持精准匹配平台的有效性：一项随机对照试验方案。

Effectiveness of an HIV peer support precision matching platform: a randomized controlled trial protocol.

机构信息

School of Nursing, Capital Medical University, Beijing, 100069, China.

School of Nursing, Peking University, No.38 Xueyuan Rd, Haidian District, Beijing, 100191, China.

出版信息

BMC Public Health. 2024 Oct 23;24(1):2938. doi: 10.1186/s12889-024-20335-w.

DOI:10.1186/s12889-024-20335-w
PMID:39443906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11515468/
Abstract

BACKGROUND: Peer support is a promising and significant way for people living with HIV (PLWH) to improve their health outcomes. Matching PLWH with HIV peer volunteers can effectively stimulate and mobilize the function of peer support in health management. We develop the online platform Aspark, which features a precision matching function for PLWH and volunteers. This protocol provides a comprehensive overview of the randomized controlled trial design based on Aspark. METHOD: A parallel randomized controlled trial using block randomization will be conducted at the Beijing YouAn Home of Loving Care. The intervention group (n = 70) will have access to all 12 features of Aspark, including precise volunteer matching, health management tools, drug interaction queries, and medication reminders. The control group (n = 70) will have access to two features of informational support on Aspark. The outcomes of both groups will be evaluated at baseline and at 3, 6, 9, and 12 months after platform registration. The primary outcome is perceived social support. The secondary outcomes include mental symptoms, quality of life, self-efficacy, medication adherence, and health behaviors. Linear mixed models or generalized linear mixed models will be applied to test the intervention effects. DISCUSSION: The Aspark trial is a randomized controlled trial designed to examine the influence of a mobile health (mHealth) application that integrates peer support and precision matching to strengthen social support for PLWH in China. This trial has the potential to significantly enhance social support for PLWH while also optimizing the delivery of peer support services and fully mobilizing the role of peer support in the overall health management of PLWH. TRIAL REGISTRATION: Clinical registration number: ChiCTR2300077454.

摘要

背景：同伴支持是提高 HIV 感染者（PLWH）健康结果的一种有前途且重要的方式。将 PLWH 与 HIV 同伴志愿者相匹配，可以有效地激发和调动同伴支持在健康管理中的作用。我们开发了在线平台 Aspark，该平台具有针对 PLWH 和志愿者的精准匹配功能。本方案提供了基于 Aspark 的随机对照试验设计的全面概述。

方法：将在北京佑安爱心家园采用区组随机化方法开展一项平行随机对照试验。干预组（n=70）将能够使用 Aspark 的全部 12 项功能，包括精准志愿者匹配、健康管理工具、药物相互作用查询和用药提醒。对照组（n=70）将能够使用 Aspark 上的两项信息支持功能。两组的结局将在平台注册后 3、6、9 和 12 个月进行评估。主要结局是感知社会支持。次要结局包括精神症状、生活质量、自我效能、药物依从性和健康行为。将应用线性混合模型或广义线性混合模型来检验干预效果。

讨论：Aspark 试验是一项随机对照试验，旨在研究一种整合同伴支持和精准匹配的移动健康（mHealth）应用程序对中国 PLWH 社会支持的影响。该试验有可能显著增强 PLWH 的社会支持，同时优化同伴支持服务的提供，并充分调动同伴支持在 PLWH 整体健康管理中的作用。

试验注册：临床试验注册号：ChiCTR2300077454。

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[1]
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Int J Nurs Sci. 2023-6-23

[2]
The effectiveness and sustainability of peer support interventions for persons living with HIV: a realist synthesis.

BMJ Glob Health. 2023-2

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Exploring core mental health symptoms among persons living with HIV: A network analysis.

Front Psychiatry. 2023-1-20

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A differentiated digital intervention to improve antiretroviral therapy adherence among men who have sex with men living with HIV in China: a randomized controlled trial.

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Psychometric properties of self-reported measures of health-related quality of life in people living with HIV: a systematic review protocol.

JBI Evid Synth. 2021-10

[10]
Cost-Effectiveness of Peer-Delivered HIV Self-Tests for MSM in Uganda.

Front Public Health. 2021

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