吉隆坡绝经期妇女激素替代疗法动态研究——一项基于社区的调查。

Exploring hormone replacement therapy dynamics among menopausal women in Kuala Lumpur - a community based survey.

机构信息

Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia.

School of Medical and Life Sciences, Sunway University, Sunway City, Malaysia.

出版信息

BMC Womens Health. 2024 Oct 23;24(1):569. doi: 10.1186/s12905-024-03358-8.

DOI:10.1186/s12905-024-03358-8

PMID:39443936

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11515679/

Abstract

BACKGROUND

Women may lack awareness of the existence of Hormone Replacement Therapy (HRT), its benefits, and potential drawbacks. Furthermore, they may be uninformed about the treatability of menopausal symptoms. Consequently, there is a need to evaluate the knowledge, attitudes, and practices related to HRT among menopausal women within the Malaysian population. Presently, no studies have reported on the inside, attitudes, and practices regarding HRT among menopausal women in Kuala Lumpur. This study sought to determine the prevalence, knowledge, attitude, and practice (KAP) towards HRT and its association with socio-demographic characteristics of the study population.

METHOD

A cross-sectional study was conducted among menopausal women (n = 404) living in Kuala Lumpur, Malaysia. Data was collected using convenient sampling. This research consists of 5 major parts which are (A) Socio-demographic characteristics of participants, (B) HRT knowledge among respondents, (C) Attitudes towards HRT, (D) Practice of HRT, and (E) Menopausal symptoms. All appropriate data from the project was analyzed using IBM SPSS Statistics Ver 26.

RESULTS

A total of 404 participants were recruited in this survey. Overall, participants had good knowledge (n = 254, 62.9%) and negative attitude (n = 213, 52.7%) towards HRT. The majority of them (83.4%) had never taken HRT. The common menopausal symptoms reported were hot flashes (35.4%), irritability/ mood swings (31.9%), and night sweats (29.2%). There was a significant association between knowledge of menopause and HRT and attitude towards HRT use. Participants (68.7%, n = 103) with poor knowledge of menopause and HRT showed a negative attitude towards HRT (p < 0.01).

CONCLUSIONS

Overall, the prevalence of HRT use among the respondents is low. 83.4% of them have never taken HRT before. There was a positive correlation between knowledge and attitude towards HRT use. Healthcare systems should educate the public using various educational tools and social media.

摘要

背景

女性可能对激素替代疗法（HRT）的存在、益处和潜在风险缺乏认识。此外，她们可能不知道绝经症状的可治疗性。因此，需要评估马来西亚人口中绝经妇女与 HRT 相关的知识、态度和实践。目前，尚无研究报告吉隆坡绝经妇女对 HRT 的内部、态度和实践。本研究旨在确定 HRT 的流行率、知识、态度和实践（KAP）及其与研究人群社会人口特征的相关性。

方法

在马来西亚吉隆坡进行了一项横断面研究，纳入了 404 名绝经妇女。数据采用便利抽样收集。本研究由 5 个主要部分组成，分别为：（A）参与者的社会人口特征；（B）受访者对 HRT 的了解；（C）对 HRT 的态度；（D）HRT 的实践；（E）绝经症状。使用 IBM SPSS Statistics Ver 26 分析项目的所有适当数据。

结果

本调查共招募了 404 名参与者。总体而言，参与者对 HRT 有较好的认识（n=254，62.9%）和消极态度（n=213，52.7%）。他们中的大多数人（83.4%）从未服用过 HRT。报告的常见绝经症状为热潮红（35.4%）、烦躁/情绪波动（31.9%）和盗汗（29.2%）。绝经和 HRT 知识与 HRT 使用态度之间存在显著相关性。绝经和 HRT 知识差的参与者（68.7%，n=103）对 HRT 持消极态度（p<0.01）。