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韩国 COVID-19 大流行期间终末期肾病患者的肾脏替代治疗趋势。

Kidney replacement therapy trends in end-stage kidney disease patients in South Korea during the COVID-19 pandemic.

机构信息

College of Pharmacy, Ajou University, Suwon, Korea.

Research Institute of Pharmaceutical Science and Technology (RIPST), Ajou University, Suwon, Korea.

出版信息

Korean J Intern Med. 2024 Nov;39(6):967-978. doi: 10.3904/kjim.2024.052. Epub 2024 Oct 24.

Abstract

BACKGROUND/AIMS: The corona virus disease 2019 posed a major risk for end-stage kidney disease (ESKD) cases. Our study aimed to assess changes in kidney replacement therapy (KRT) trends and healthcare access for these patients during the pandemic.

METHODS

We retrospectively analyzed nationwide data from July 2017 to June 2022 to assess changes in KRT and ESKD incidence. KRT modalities included peritoneal dialysis (PD), hemodialysis (HD), and kidney transplantation (KT). We utilized the interrupted time series (ITS) method to compare changes in KRT modality before and after the incidence of the COVID-19 pandemic.

RESULTS

ESKD incidence remained stable from 2018 to April 2022. The ITS analysis confirmed that the pandemic did not significant impact overall KRT incidence. PD cases decreased (5.7% to 1.3%), while HD cases increased (81.6% to 85%), and KT recipient remained relatively stable (12.7% to 17.3%). The hospitalization and hospital stay decreased in nursing hospital (165.01 days to 147.77 days) and general hospital (61.34 days to 55.58 days) during the pandemic, however, remained unchanged for PD and KT.

CONCLUSION

Our findings indicate no significant changes in ESKD incidence in South Korea during the pandemic. However, there were shifts in modality distribution, with decreased PD and increased HD cases. Notably, HD cases showed a significant reduction in hospital admissions and length of stay. The healthcare system demonstrated stability during the pandemic, with minimal disruptions in ESKD care.

摘要

背景/目的:2019 年冠状病毒病 (COVID-19) 对终末期肾病 (ESKD) 患者构成重大风险。本研究旨在评估大流行期间这些患者的肾脏替代治疗 (KRT) 趋势和医疗保健机会的变化。

方法

我们回顾性分析了 2017 年 7 月至 2022 年 6 月的全国性数据,以评估 KRT 和 ESKD 发病率的变化。KRT 方式包括腹膜透析 (PD)、血液透析 (HD) 和肾脏移植 (KT)。我们利用中断时间序列 (ITS) 方法比较 COVID-19 大流行前后 KRT 方式的变化。

结果

ESKD 发病率从 2018 年到 2022 年 4 月保持稳定。ITS 分析证实,大流行对总体 KRT 发病率没有显著影响。PD 病例减少(5.7%至 1.3%),而 HD 病例增加(81.6%至 85%),KT 受体保持相对稳定(12.7%至 17.3%)。在疗养院(165.01 天至 147.77 天)和综合医院(61.34 天至 55.58 天),住院和住院时间在大流行期间减少,但 PD 和 KT 保持不变。

结论

我们的研究结果表明,韩国在大流行期间 ESKD 发病率没有显著变化。然而,模式分布发生了变化,PD 减少,HD 增加。值得注意的是,HD 病例的住院和住院时间显著减少。大流行期间医疗保健系统保持稳定,ESKD 护理基本没有中断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2be/11569916/a76fedb292aa/kjim-2024-052f1.jpg

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