da Silva Jéssica Daniel Martins, Pereira Lucas Borges, Varallo Fabiana Rossi, do Nascimento Mariana Martins Gonzaga, Torres Larissa Helena, Maia Paulo Roberto, Ceron Carla Speroni, Dos Reis Tiago Marques
Faculty of Pharmaceutical Sciences, Federal University of Alfenas, Alfenas, Minas Gerais, Brazil.
Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Braz J Microbiol. 2024 Dec;55(4):3899-3908. doi: 10.1007/s42770-024-01540-6. Epub 2024 Oct 24.
Antimicrobial Stewardship Programs (ASPs) are associated with positive outcomes, but seem to be consolidated in few hospitals. This study aimed to evaluate ASPs in Brazilian hospitals and the barriers to their consolidation from the pharmacists' perspective. This is a cross-sectional study. Data were collected through an online questionnaire applied to hospital pharmacists. Data analysis was performed by descriptive statistics and Spearman's ordinal correlation test. A total of 83 pharmacists participated in the study and 45.8% stated that the hospital in which they worked had an ASP. The ASPs were predominantly implemented in public hospitals, with a greater number of beds in the intensive care unit and beds in general. The main barriers to the consolidation of ASPs were: reduced number of pharmacists, time allocated to other demands of the pharmacy, the ineffectiveness of the communication process with doctors, and lack of access to reliable information about antimicrobials in the hospital. Pharmacists that work in hospitals where ASPs were implemented were more confident (p = 0.000) and with a better perception of the barriers that prevent their consolidation (p = 0.003. The ASP was commonly adopted in public hospitals with a greater number of beds. The main obstacles to consolidation were infrastructure, economic, and educational resources.
抗菌药物管理计划(ASPs)与积极的结果相关,但似乎仅在少数医院得到巩固。本研究旨在从药剂师的角度评估巴西医院的抗菌药物管理计划及其巩固过程中的障碍。这是一项横断面研究。通过向医院药剂师发放在线问卷收集数据。数据分析采用描述性统计和Spearman等级相关检验。共有83名药剂师参与了该研究,45.8%的人表示他们工作的医院设有抗菌药物管理计划。抗菌药物管理计划主要在公立医院实施,重症监护病房和普通病房的床位数量较多。抗菌药物管理计划巩固过程中的主要障碍包括:药剂师数量减少、分配给药房其他需求的时间、与医生沟通流程的无效性以及无法获取医院内有关抗菌药物的可靠信息。在实施了抗菌药物管理计划的医院工作的药剂师更有信心(p = 0.000),并且对阻碍其巩固的障碍有更好的认知(p = 0.003)。抗菌药物管理计划通常在床位较多的公立医院采用。巩固过程中的主要障碍是基础设施、经济和教育资源。