流行率-缺乏 pertactin 的百日咳鲍特菌分离株，斯洛文尼亚。
Prevalence of Pertactin-Deficient Bordetella pertussis Isolates, Slovenia.
出版信息
Emerg Infect Dis. 2024 Nov;30(11):2429-2432. doi: 10.3201/eid3011.231393.
Abstract
In Slovenia, primary acellular pertussis vaccines (ACVs) containing pertactin (PRN) were mostly used during 1999-2016; ACVs without PRN were introduced in 2017. Among 123 Bordetella pertussis strains collected during 2002-2020, a total of 48 were PRN-deficient; 44 were collected after 2017. Changes to ACVs could increase PRN-deficient B. pertussis and infections.
摘要
在斯洛文尼亚，1999 年至 2016 年期间主要使用含有百日咳丝状血凝素（PRN）的单价无细胞百日咳疫苗（ACV）；2017 年引入了不含 PRN 的 ACV。在 2002 年至 2020 年间收集的 123 株百日咳博德特氏菌中，共有 48 株 PRN 缺失；其中 44 株是在 2017 年后收集的。ACV 的变化可能会增加 PRN 缺失的百日咳博德特氏菌和感染。
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