Hiramatsu Yukihiro, Miyaji Yusuke, Otsuka Nao, Arakawa Yoshichika, Shibayama Keigo, Kamachi Kazunari
Emerg Infect Dis. 2017 Apr;23(4):699-701. doi: 10.3201/eid2304.161575.
Prevalence of pertactin-lacking Bordetella pertussis isolates has been observed worldwide. In Japan, however, we found that the frequency of pertactin-deficient isolates in 2014-2016 (8%) was significantly lower than the frequency in 2005-2007 (41%), 2008-2010 (35%), and 2011-2013 (25%). This reduction was closely associated with changes in genotypes.
在全球范围内都观察到了缺乏百日咳杆菌粘附素的百日咳博德特氏菌分离株的流行情况。然而,在日本,我们发现2014 - 2016年缺乏百日咳杆菌粘附素的分离株频率(8%)显著低于2005 - 2007年(41%)、2008 - 2010年(35%)和2011 - 2013年(25%)。这种减少与基因型的变化密切相关。