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肯尼亚加里萨县转诊医院收治的6至59个月大儿童中消瘦与体重不足及发育迟缓并存的情况。

Wasting coexisting with underweight and stunting among children aged 6‒59 months hospitalised in Garissa County Referral Hospital, Kenya.

作者信息

Wambua Mutuvi, Kariuki Symon M, Abdullahi Hassan, Abdullahi Osman A, Ngari Moses M

机构信息

Department of Public Health, Pwani University, Kilifi, Kenya.

KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya.

出版信息

Matern Child Nutr. 2025 Jan;21(1):e13754. doi: 10.1111/mcn.13754. Epub 2024 Oct 24.

Abstract

Management of undernourished children depends only on wasting yet it can coexist with underweight and/or stunting. Among children admitted to hospital with acute illness, we determined the proportion with wasting coexisting with underweight and/or stunting and their risk factors. A retrospective review of hospital records of children 6‒59 months old admitted at Garissa County referral hospital, Kenya, from January 2017 to December 2019 was conducted. Using World Health Organization 2006 growth standards, undernutrition were defined: wasting as Weight-for-height Z-score < -2, stunting Height-for-age Z-score < -2 and underweight Weight-for-age Z-score < -2. We studied wasting coexisting with underweight and/or stunting. Among 624 children recruited, 347 (56%) were males and 511 (82%) <24 months old. Diarrhoea 210 (34%) and pallor/anaemia 310 (50%) were the most frequent admission diagnosis. HIV infection was present among 8 (1.3%) children. Wasting, underweight and stunting were present among 595 (95%), 518 (83%) and 176 (28%) children respectively. 161 (26%), 506 (81%) and 161 (26%) children had wasting coexisting with stunting, underweight and both stunting and underweight respectively. In the multivariable regression, diarrhoea was positively associated with wasting coexisting with stunting (adjusted risk ratio [aRR = 2.96] [95% CI = 2.06‒4.23]) and anaemia with wasting coexisting with underweight (aRR = 1.23) (95% CI = 1.03‒1.47). Overall, 343 (55%) children were discharged alive, 67 (11%) absconded from the wards, 164 (26%) were transferred to another hospital and 50 (8.0%) died before discharge. The risk of inpatient death was 10.3%, 7.9%, 8.4% and 6.8% among children not wasted, wasted only, wasted & underweight, and wasted and underweight and stunted respectively (Chi-square p = 0.60). The study reports an unacceptably high levels of undernourishment, including coexisting forms of undernutrition among hospitalised children. This highlights a public health priority for current nutrition therapeutic care and need of continuity of care among those children discharged alive in the community-based management of acute malnutrition programmes.

摘要

营养不良儿童的管理仅取决于消瘦情况,然而消瘦可能与体重不足和/或发育迟缓同时存在。在因急性疾病入院的儿童中,我们确定了消瘦与体重不足和/或发育迟缓同时存在的比例及其风险因素。对2017年1月至2019年12月在肯尼亚加里萨县转诊医院住院的6至59个月大儿童的医院记录进行了回顾性研究。采用世界卫生组织2006年生长标准,对营养不良进行定义:消瘦为身高别体重Z评分<-2,发育迟缓为年龄别身高Z评分<-2,体重不足为年龄别体重Z评分<-2。我们研究了消瘦与体重不足和/或发育迟缓同时存在的情况。在招募的624名儿童中,347名(56%)为男性,511名(82%)年龄<24个月。腹泻210例(34%)和面色苍白/贫血310例(50%)是最常见的入院诊断。8名(1.3%)儿童感染了艾滋病毒。消瘦、体重不足和发育迟缓分别出现在595名(95%)、518名(83%)和176名(28%)儿童中。分别有161名(26%)、506名(81%)和161名(26%)儿童消瘦与发育迟缓、体重不足以及发育迟缓和体重不足同时存在。在多变量回归分析中,腹泻与消瘦合并发育迟缓呈正相关(调整风险比[aRR = 2.96] [95%置信区间 = 2.06 - 4.23]),贫血与消瘦合并体重不足呈正相关(aRR = 1.23)(95%置信区间 = 1.03 - 1.47)。总体而言,343名(55%)儿童存活出院,67名(11%)擅自离院,164名(26%)转至其他医院,50名(8.0%)在出院前死亡。未消瘦、仅消瘦、消瘦且体重不足、消瘦且体重不足和发育迟缓的儿童住院死亡风险分别为10.3%、7.9%、8.4%和6.8%(卡方检验p = 0.60)。该研究报告了住院儿童中营养不良水平高得令人无法接受,包括同时存在的多种营养不良形式。这凸显了当前营养治疗护理的公共卫生重点以及在社区急性营养不良项目中对存活出院儿童进行持续护理的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56b1/11650073/1fcdc5b936d1/MCN-21-e13754-g003.jpg

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